COVID-19: Mechanistic model calibration subject to active and varying non-pharmaceutical interventions

• Published in: Chemical engineering science Vol. 231; p. 116330
• Main Authors: Willis, Mark J., Wright, Allen, Bramfitt, Victoria, Díaz, Victor Hugo Grisales
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 15.02.2021
• Subjects: COVID-19; Discrete event modelling and management; Model calibration; Time varying disease transmission rate; COVID-19; Discrete event modelling and management; Model calibration; Time varying disease transmission rate

•Established chemical engineering modelling practice applied to COVID 19 Re estimation.•Effective reproduction number modelled as time varying stoichiometry in kinetic model.•Model uses piecewise continuous integration and event and discontinuity management.•Nested optimiser algorithm to estimate Re...