Adiponectin and resistin in PCOS: a clinical, biochemical and molecular genetic study

• Published in: Human reproduction (Oxford) Vol. 21; no. 9; pp. 2257 - 2265
• Main Authors: Escobar-Morreale, H.F., Villuendas, G., Botella-Carretero, J.I., Álvarez-Blasco, F., Sanchón, R., Luque-Ramírez, M., San Millán, J.L.
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.09.2006; Oxford Publishing Limited (England)
• Subjects: Adiponectin - blood; Adiponectin - genetics; Adult; Biological and medical sciences; Blood Pressure; Case-Control Studies; Cross-Sectional Studies; Female; Genotype; Gynecology. Andrology. Obstetrics; Humans; Insulin Resistance; Medical sciences; Obesity; Polycystic Ovary Syndrome - blood; Polycystic Ovary Syndrome - genetics; Polymorphism, Genetic; Resistin - blood; Resistin - genetics; adiponectin; resistin; adipokines; insulin resistance; polycystic ovary syndrome; Endocrinopathy; Adipocytokine; Female sterility; Biochemistry; Adipokine; Polycystic ovary; Female genital diseases; Adiponectin; Ovarian diseases; Target tissue resistance; Symptomatology; adiponectin/adipokines/insulin resistance/polycystic ovary syndrome/resistin; Vertebrata; Mammalia; Cyst; Genetics; Insulin resistance; Benign neoplasm; Molecular biology; Resistin
• ISSN: 0268-1161; 1460-2350
• DOI: 10.1093/humrep/del146

We conducted a cross-sectional case–control study to evaluate the possible involvement of adiponectin and resistin in the pathogenesis of polycystic ovary syndrome (PCOS). METHODS: Seventy-six PCOS patients and 40 non-hyperandrogenic women matched for BMI and degree of obesity were included. Serum a...