Deconstructing gastrulation at single-cell resolution

• Published in: Current biology Vol. 32; no. 8; pp. 1861 - 1868.e7
• Main Authors: Stern, Tomer, Shvartsman, Stanislav Y., Wieschaus, Eric F.
• Format: Journal Article
• Language: English
• Published: England Elsevier Inc 25.04.2022
• Subjects: Animals; Cell Shape; Drosophila; Embryo, Mammalian; Gastrulation; Morphogenesis
• ISSN: 0960-9822; 1879-0445; 1879-0445
• DOI: 10.1016/j.cub.2022.02.059

Gastrulation movements in all animal embryos start with regulated deformations of patterned epithelial sheets, which are driven by cell divisions, cell shape changes, and cell intercalations. Each of these behaviors has been associated with distinct aspects of gastrulation1–4 and has been a subject...