Mesenchymal-epithelial interaction regulates gastrointestinal tract development in mouse embryos

• Published in: Cell reports (Cambridge) Vol. 40; no. 2; p. 111053
• Main Authors: Zhao, Lianzheng, Song, Wanlu, Chen, Ye-Guang
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 12.07.2022
• Subjects: development; intestine; mesenchymal-epithelial interaction; single-cell RNA-seq; spatial RNA-seq; stomach; mesenchymal-epithelial interaction; development; intestine; single-cell RNA-seq; stomach; CP: Developmental biology; spatial RNA-seq

After gut tube patterning in early embryos, the cellular and molecular changes of developing stomach and intestine remain largely unknown. Here, combining single-cell RNA sequencing and spatial RNA sequencing, we construct a spatiotemporal transcriptomic landscape of the mouse stomach and intestine...