Early administration of remdesivir plus convalescent plasma therapy is effective to treat COVID-19 pneumonia in B-cell depleted patients with hematological malignancies

• Published in: Annals of hematology Vol. 101; no. 10; pp. 2337 - 2345
• Main Authors: Magyari, Ferenc, Pinczés, László Imre, Páyer, Edit, Farkas, Katalin, Ujfalusi, Szilvia, Diószegi, Ágnes, Sik, Máté, Simon, Zsófia, Nagy, Gergely, Hevessy, Zsuzsanna, Nagy, Béla, Illés, Árpád
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.10.2022; Springer Nature B.V
• Subjects: Antiviral drugs; Coronaviruses; COVID-19; Hematology; Medicine; Medicine & Public Health; Oncology; Original; Original Article; Pneumonia; Severe acute respiratory syndrome coronavirus 2; COVID-19; Convalescent plasma treatment; SARS-CoV-2; Remdesivir; Hematological malignancies; Immunodeficiency

Patients with hematological malignancies (HMs) are at a higher risk of developing severe form and protracted course of COVID-19 disease. We investigated whether the combination of viral replication inhibition with remdesivir and administration of anti-SARS-CoV-2 immunoglobulins with convalescent pla...