Compartmentalized PGRP expression along the dipteran Bactrocera dorsalis gut forms a zone of protection for symbiotic bacteria

All metazoan guts are subject to opposing pressures wherein the immune system must eliminate pathogens while tolerating the presence of symbiotic microbiota. The Imd pathway is an essential defense against invading pathogens in insect guts, but tolerance mechanisms are less understood. Here, we find...

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Published inCell reports (Cambridge) Vol. 41; no. 3; p. 111523
Main Authors Yao, Zhichao, Cai, Zhaohui, Ma, Qiongke, Bai, Shuai, Wang, Yichen, Zhang, Ping, Guo, Qiongyu, Gu, Jian, Lemaitre, Bruno, Zhang, Hongyu
Format Journal Article
LanguageEnglish
Published Elsevier Inc 18.10.2022
Subjects
Bactrocera dorsalis
gut microbiota
Imd pathway
immune genes
PGRPs
CP: Immunology
immune genes
PGRPs
CP: Microbiology
Imd pathway
gut microbiota
Bactrocera dorsalis
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Abstract All metazoan guts are subject to opposing pressures wherein the immune system must eliminate pathogens while tolerating the presence of symbiotic microbiota. The Imd pathway is an essential defense against invading pathogens in insect guts, but tolerance mechanisms are less understood. Here, we find PGRP-LB and PGRP-SB express mainly in the anterior and middle midgut in a similar pattern to symbiotic Enterobacteriaceae bacteria along the Bactrocera dorsalis gut. Knockdown of PGRP-LB and PGRP-SB enhances the expression of antimicrobial peptide genes and reduces Enterobacteriaceae numbers while increasing abundance of opportunistic pathogens. Microbiota numbers recover to normal levels after the RNAi effect subsided. In contrast, high expression of PGRP-LC in the foregut allows increased antibacterial peptide production to efficiently filter the entry of pathogens, protecting the symbiotic bacteria. Our study describes a mechanism by which regional expression of PGRPs construct a protective zone for symbiotic microbiota while maintaining the ability to fight pathogens. [Display omitted] •Symbiotic bacteria are mainly located in the anterior midgut of B. dorsalis•Regional expression of PGRP matches the distribution pattern of symbiotic bacteria•PGRP-LB and PGRP-SB establish a protective zone for symbiotic bacteria colonization•PGRP-LC and AMPs in the foregut filter the pathogens to protect symbiotic bacteria Yao et al. find there is a regional expression of PGPR and spatial distribution of symbiotic bacteria along the Bactrocera dorsalis gut. This regional expression of PGPR tightly regulates the Imd pathway to construct a protective zone for symbiotic microbiota while maintaining the ability to fight pathogens.
AbstractList All metazoan guts are subject to opposing pressures wherein the immune system must eliminate pathogens while tolerating the presence of symbiotic microbiota. The Imd pathway is an essential defense against invading pathogens in insect guts, but tolerance mechanisms are less understood. Here, we find PGRP-LB and PGRP-SB express mainly in the anterior and middle midgut in a similar pattern to symbiotic Enterobacteriaceae bacteria along the Bactrocera dorsalis gut. Knockdown of PGRP-LB and PGRP-SB enhances the expression of antimicrobial peptide genes and reduces Enterobacteriaceae numbers while increasing abundance of opportunistic pathogens. Microbiota numbers recover to normal levels after the RNAi effect subsided. In contrast, high expression of PGRP-LC in the foregut allows increased antibacterial peptide production to efficiently filter the entry of pathogens, protecting the symbiotic bacteria. Our study describes a mechanism by which regional expression of PGRPs construct a protective zone for symbiotic microbiota while maintaining the ability to fight pathogens.All metazoan guts are subject to opposing pressures wherein the immune system must eliminate pathogens while tolerating the presence of symbiotic microbiota. The Imd pathway is an essential defense against invading pathogens in insect guts, but tolerance mechanisms are less understood. Here, we find PGRP-LB and PGRP-SB express mainly in the anterior and middle midgut in a similar pattern to symbiotic Enterobacteriaceae bacteria along the Bactrocera dorsalis gut. Knockdown of PGRP-LB and PGRP-SB enhances the expression of antimicrobial peptide genes and reduces Enterobacteriaceae numbers while increasing abundance of opportunistic pathogens. Microbiota numbers recover to normal levels after the RNAi effect subsided. In contrast, high expression of PGRP-LC in the foregut allows increased antibacterial peptide production to efficiently filter the entry of pathogens, protecting the symbiotic bacteria. Our study describes a mechanism by which regional expression of PGRPs construct a protective zone for symbiotic microbiota while maintaining the ability to fight pathogens.
All metazoan guts are subject to opposing pressures wherein the immune system must eliminate pathogens while tolerating the presence of symbiotic microbiota. The Imd pathway is an essential defense against invading pathogens in insect guts, but tolerance mechanisms are less understood. Here, we find PGRP-LB and PGRP-SB express mainly in the anterior and middle midgut in a similar pattern to symbiotic Enterobacteriaceae bacteria along the Bactrocera dorsalis gut. Knockdown of PGRP-LB and PGRP-SB enhances the expression of antimicrobial peptide genes and reduces Enterobacteriaceae numbers while increasing abundance of opportunistic pathogens. Microbiota numbers recover to normal levels after the RNAi effect subsided. In contrast, high expression of PGRP-LC in the foregut allows increased antibacterial peptide production to efficiently filter the entry of pathogens, protecting the symbiotic bacteria. Our study describes a mechanism by which regional expression of PGRPs construct a protective zone for symbiotic microbiota while maintaining the ability to fight pathogens. [Display omitted] •Symbiotic bacteria are mainly located in the anterior midgut of B. dorsalis•Regional expression of PGRP matches the distribution pattern of symbiotic bacteria•PGRP-LB and PGRP-SB establish a protective zone for symbiotic bacteria colonization•PGRP-LC and AMPs in the foregut filter the pathogens to protect symbiotic bacteria Yao et al. find there is a regional expression of PGPR and spatial distribution of symbiotic bacteria along the Bactrocera dorsalis gut. This regional expression of PGPR tightly regulates the Imd pathway to construct a protective zone for symbiotic microbiota while maintaining the ability to fight pathogens.
ArticleNumber 111523
Author Cai, Zhaohui
Lemaitre, Bruno
Bai, Shuai
Guo, Qiongyu
Yao, Zhichao
Ma, Qiongke
Gu, Jian
Wang, Yichen
Zhang, Ping
Zhang, Hongyu
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  surname: Wang
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  organization: Key Laboratory of Horticultural Plant Biology (MOE), Hubei Hongshan Laboratory, Institute of Urban and Horticultural Entomology, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan, People’s Republic of China
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  surname: Zhang
  fullname: Zhang, Hongyu
  email: hongyu.zhang@mail.hzau.edu.cn
  organization: Key Laboratory of Horticultural Plant Biology (MOE), Hubei Hongshan Laboratory, Institute of Urban and Horticultural Entomology, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan, People’s Republic of China
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Cites_doi 10.1073/pnas.1116932108
10.1038/nri2515
10.1016/j.celrep.2015.08.004
10.3389/fmicb.2017.00801
10.1038/ncomms8618
10.1111/1744-7917.12986
10.1016/j.mib.2010.10.003
10.1074/jbc.M208900200
10.1074/jbc.M313856200
10.1038/ncomms15186
10.1038/ismej.2015.202
10.1073/pnas.1701819114
10.1038/ismej.2013.134
10.1371/journal.ppat.1001097
10.1016/j.immuni.2011.09.018
10.1016/j.cub.2021.02.046
10.1016/j.ibmb.2007.10.003
10.1038/nbt.1883
10.1016/j.immuni.2006.02.012
10.1264/jsme2.ME11325
10.1016/j.chom.2017.12.007
10.1016/j.bbrc.2006.09.139
10.1111/eva.12698
10.1016/j.cell.2019.07.029
10.1038/nrmicro2894
10.1371/journal.pone.0017231
10.1128/mBio.00824-21
10.1146/annurev.ento.49.061802.123416
10.1038/nrmicro3552
10.1016/j.cmet.2017.11.011
10.1016/j.celrep.2013.04.001
10.1146/annurev.ento.50.071803.130428
10.1073/pnas.1009473107
10.3390/cells11010152
10.1006/meth.2001.1262
10.1126/science.1212782
10.1186/1471-2105-12-323
10.4049/jimmunol.1201022
10.7554/eLife.00886
10.1016/j.cell.2013.04.009
10.1016/j.chom.2019.02.003
10.7554/eLife.44341
10.1016/S0167-7012(00)00152-4
10.1128/AEM.01843-08
10.1016/j.immuni.2018.09.017
10.14806/ej.17.1.200
10.1128/AEM.07810-11
10.1111/1574-6976.12025
10.1111/j.1365-2672.2011.05001.x
10.1038/nmicrobiol.2017.20
10.1186/s13068-018-1015-1
10.1038/nrmicro3074
10.1016/j.chom.2012.06.002
10.1016/j.cell.2013.12.018
10.1002/ps.3528
10.1371/journal.pbio.2005710
10.1126/science.1149357
10.1146/annurev.immunol.25.022106.141615
10.1038/nmicrobiol.2016.23
10.1016/j.cub.2020.08.080
10.1146/annurev-ento-011019-025224
10.1111/1751-7915.12323
10.1093/jee/toaa294
10.1128/mBio.01117-14
10.1186/s40168-017-0236-z
10.1016/j.chom.2010.07.005
10.1126/scisignal.2003970
10.1371/journal.ppat.1008441
10.1016/j.chom.2016.01.008
10.1371/journal.ppat.0020056
10.1128/AEM.70.6.3575-3581.2004
10.1371/journal.ppat.0020014
10.1128/AEM.00803-19
10.1371/journal.pone.0017788
10.1093/genetics/iyab188
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Keywords CP: Immunology
immune genes
PGRPs
CP: Microbiology
Imd pathway
gut microbiota
Bactrocera dorsalis
Language English
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References Yao, Wang, Li, Cai, Lemaitre, Zhang (bib72) 2016; 10
Bruno, Bonelli, De Filippis, Di Lelio, Tettamanti, Casartelli, Ercolini, Caccia (bib4) 2018; 85
Hudry, de Goeij, Mineo, Gaspar, Hadjieconomou, Studd, Mokochinski, Kramer, Plaçais, Preat, Miguel-Aliaga (bib30) 2019; 178
Zheng, Powell, Steele, Dietrich, Moran (bib77) 2017; 114
Matsuda, Tsuji, Asahara, Matsumoto, Takada, Nomoto (bib45) 2009; 75
Pan, Zhou, Wu, Bian, Lu, Raikhel, Xi (bib52) 2012; 109
Saha, Jing, Park, Wang, Li, Gupta, Dziarski (bib59) 2010; 8
Engel, Moran (bib22) 2013; 37
Martinson, Moy, Moran (bib44) 2012; 78
Pais, Valente, Sporniak, Teixeira (bib32) 2018; 16
Cheng, Guo, Riegler, Xi, Liang, Xu (bib15) 2017; 5
Mellroth, Karlsson, Steiner (bib46) 2003; 278
Tanji, Yun, Ip (bib66) 2010; 107
Chen, Luan, Liu, Wang, Chang, Snijders, Mao, Secombe, Dan, Chen (bib13) 2019; 25
Zaidman-Rémy, Poidevin, Hervé, Welchman, Paredes, Fahlander, Steiner, Mengin-Lecreulx, Lemaitre (bib74) 2011; 6
Guo, Karpac, Tran, Jasper (bib25) 2013; 156
Li, Ren, Xie, Gao, He, Hassan, Lu, Cheng (bib37) 2020; 30
Stecher, Hardt (bib64) 2011; 14
Donaldson, Lee, Mazmanian (bib20) 2016; 14
Buchon, Broderick, Lemaitre (bib6) 2013; 11
Grabherr, Haas, Yassour, Levin, Thompson, Amit, Adiconis, Fan, Raychowdhury, Zeng (bib24) 2011; 29
Round, Mazmanian (bib57) 2009; 9
Thong-On, Suzuki, Noda, Inoue, Kajiwara, Ohkuma (bib67) 2012; 27
Bosco-Drayon, Poidevin, Boneca, Narbonne-Reveau, Royet, Charroux (bib3) 2012; 12
Guo, Yao, Cai, Bai, Zhang (bib26) 2022; 29
Li, Qi, Jasper (bib36) 2016; 19
Smith, Srygley, Healy, Swaminath, Mueller (bib63) 2017; 8
Singh, Bhunia (bib62) 2016; 9
Shin, Kim, You, Kim, Kim, Lee, Yoon, Ryu, Lee (bib61) 2011; 334
Vogel, Shukla, Engl, Weiss, Fischer, Steiger, Heckel, Kaltenpoth, Vilcinskas (bib68) 2017; 8
Ren, Ma, Xie, Lu, Cheng (bib56) 2021; 31
Hedengren-Olcott, Olcott, Mooney, Ekengren, Geller, Taylor (bib28) 2004; 279
Marra, Hanson, Kondo, Erkosar, Lemaitre (bib42) 2021; 12
Ceja-Navarro, Nguyen, Karaoz, Gross, Herman, Andersen, Bruns, Pett-Ridge, Blackwell, Brodie (bib10) 2014; 8
Zhang, Yao, Bai, Zhang (bib75) 2022; 11
Lemaitre, Hoffmann (bib34) 2007; 25
Wang, Jin, Peng, Zhang, Chen, Hua (bib69) 2014; 70
Wang, Jin, Zhang (bib70) 2011; 110
Raza, Wang, Cai, Bai, Yao, Awan, Zhang, Zheng, Zhang (bib55) 2020; 16
Zaidman-Rémy, Hervé, Poidevin, Pili-Floury, Kim, Blanot, Oh, Ueda, Mengin-Lecreulx, Lemaitre (bib73) 2006; 24
Zhang, Cai, Wang, Liu, Lin, Hua, Zhang, Yi, Song, Ji (bib76) 2021; 114
Buchon, Osman, David, Fang, Boquete, Deplancke, Lemaitre (bib7) 2013; 3
Shibata, Sekihara, Fujikawa, Miyaji, Maki, Ishihara, Koshiba, Kawabata (bib60) 2013; 6
Li, Dewey (bib35) 2011; 12
Marianes, Spradling (bib41) 2013; 2
Clark, Salazar, Yamada, Fitz-Gibbon, Morselli, Alcaraz, Rana, Rera, Pellegrini, Ja, Walker (bib17) 2015; 12
Li, Zhang, Zhang (bib38) 2011; 6
Iatsenko, Boquete, Lemaitre (bib31) 2018; 49
Endt, Stecher, Chaffron, Slack, Tchitchek, Benecke, Van Maele, Sirard, Mueller, Heikenwalder (bib21) 2010; 6
Moter, Göbel (bib48) 2000; 41
Broderick, Buchon, Lemaitre (bib5) 2014; 5
Martin (bib43) 2011; 17
Ceja-Navarro, Vega, Karaoz, Hao, Jenkins, Lim, Kosina, Infante, Northen, Brodie (bib11) 2015; 6
Neyen, Poidevin, Roussel, Lemaitre (bib49) 2012; 189
Davidson, Oshlack (bib18) 2014; 15
Livak, Schmittgen (bib40) 2001; 25
Dillon, Dillon (bib19) 2004; 49
Geng, Cheng, Wang, Zhu, Le, Wu, Xie, Yuan, Sun (bib23) 2018; 11
Storelli, Strigini, Grenier, Bozonnet, Schwarzer, Daniel, Matos, Leulier (bib65) 2018; 27
Cai, Yao, Li, Xi, Bourtzis, Zhao, Bai, Zhang (bib9) 2018; 11
Huang, Li, Ren, Cheng (bib29) 2019; 85
Pang, Xiao, Liu, Zhang, Liu, Liu, Wang, Cheng (bib53) 2016; 1
Paredes, Welchman, Poidevin, Lemaitre (bib54) 2011; 35
Bischoff, Vignal, Duvic, Boneca, Hoffmann, Royet (bib2) 2006; 2
Ryu, Kim, Lee, Bai, Nam, Bae, Lee, Shin, Ha, Lee (bib58) 2008; 319
Chen, Dai, Lu, Chang (bib14) 2008; 38
Clarke, Armstrong, Carmichael, Milne, Raghu, Roderick, Yeates (bib16) 2005; 50
Nyholm, Graf (bib50) 2012; 10
Xiao, Yang, Pang, Zhang, Zhu, Wang, Gao, Cheng (bib71) 2017; 2
Mellroth, Steiner (bib47) 2006; 350
Charroux, Capo, Kurz, Peslier, Chaduli, Viallat-Lieutaud, Royet (bib12) 2018; 23
Lee, Kim, Kim, Ha, You, Kim, Kim, Kwon, Ryu, Lee (bib33) 2013; 153
Liehl, Blight, Vodovar, Boccard, Lemaitre (bib39) 2006; 2
Carboni, Hanson, Lindsay, Wasserman, Lemaitre (bib8) 2022; 220
Hanson, Dostálová, Ceroni, Poidevin, Kondo, Lemaitre (bib27) 2019; 8
Bartosch, Fite, Macfarlane, McMurdo (bib1) 2004; 70
Zhu, Palli (bib78) 2020; 65
Raza (10.1016/j.celrep.2022.111523_bib55) 2020; 16
Round (10.1016/j.celrep.2022.111523_bib57) 2009; 9
Bruno (10.1016/j.celrep.2022.111523_bib4) 2018; 85
Lemaitre (10.1016/j.celrep.2022.111523_bib34) 2007; 25
Li (10.1016/j.celrep.2022.111523_bib36) 2016; 19
Mellroth (10.1016/j.celrep.2022.111523_bib47) 2006; 350
Hudry (10.1016/j.celrep.2022.111523_bib30) 2019; 178
Ceja-Navarro (10.1016/j.celrep.2022.111523_bib10) 2014; 8
Zaidman-Rémy (10.1016/j.celrep.2022.111523_bib73) 2006; 24
Zhang (10.1016/j.celrep.2022.111523_bib75) 2022; 11
Martinson (10.1016/j.celrep.2022.111523_bib44) 2012; 78
Clark (10.1016/j.celrep.2022.111523_bib17) 2015; 12
Endt (10.1016/j.celrep.2022.111523_bib21) 2010; 6
Donaldson (10.1016/j.celrep.2022.111523_bib20) 2016; 14
Iatsenko (10.1016/j.celrep.2022.111523_bib31) 2018; 49
Hanson (10.1016/j.celrep.2022.111523_bib27) 2019; 8
Guo (10.1016/j.celrep.2022.111523_bib25) 2013; 156
Yao (10.1016/j.celrep.2022.111523_bib72) 2016; 10
Cai (10.1016/j.celrep.2022.111523_bib9) 2018; 11
Smith (10.1016/j.celrep.2022.111523_bib63) 2017; 8
Charroux (10.1016/j.celrep.2022.111523_bib12) 2018; 23
Hedengren-Olcott (10.1016/j.celrep.2022.111523_bib28) 2004; 279
Grabherr (10.1016/j.celrep.2022.111523_bib24) 2011; 29
Ren (10.1016/j.celrep.2022.111523_bib56) 2021; 31
Cheng (10.1016/j.celrep.2022.111523_bib15) 2017; 5
Bartosch (10.1016/j.celrep.2022.111523_bib1) 2004; 70
Vogel (10.1016/j.celrep.2022.111523_bib68) 2017; 8
Li (10.1016/j.celrep.2022.111523_bib35) 2011; 12
Bischoff (10.1016/j.celrep.2022.111523_bib2) 2006; 2
Matsuda (10.1016/j.celrep.2022.111523_bib45) 2009; 75
Marra (10.1016/j.celrep.2022.111523_bib42) 2021; 12
Shibata (10.1016/j.celrep.2022.111523_bib60) 2013; 6
Xiao (10.1016/j.celrep.2022.111523_bib71) 2017; 2
Zheng (10.1016/j.celrep.2022.111523_bib77) 2017; 114
Clarke (10.1016/j.celrep.2022.111523_bib16) 2005; 50
Wang (10.1016/j.celrep.2022.111523_bib69) 2014; 70
Geng (10.1016/j.celrep.2022.111523_bib23) 2018; 11
Zhang (10.1016/j.celrep.2022.111523_bib76) 2021; 114
Chen (10.1016/j.celrep.2022.111523_bib14) 2008; 38
Davidson (10.1016/j.celrep.2022.111523_bib18) 2014; 15
Lee (10.1016/j.celrep.2022.111523_bib33) 2013; 153
Pan (10.1016/j.celrep.2022.111523_bib52) 2012; 109
Paredes (10.1016/j.celrep.2022.111523_bib54) 2011; 35
Pang (10.1016/j.celrep.2022.111523_bib53) 2016; 1
Carboni (10.1016/j.celrep.2022.111523_bib8) 2022; 220
Li (10.1016/j.celrep.2022.111523_bib38) 2011; 6
Martin (10.1016/j.celrep.2022.111523_bib43) 2011; 17
Zhu (10.1016/j.celrep.2022.111523_bib78) 2020; 65
Li (10.1016/j.celrep.2022.111523_bib37) 2020; 30
Storelli (10.1016/j.celrep.2022.111523_bib65) 2018; 27
Huang (10.1016/j.celrep.2022.111523_bib29) 2019; 85
Ryu (10.1016/j.celrep.2022.111523_bib58) 2008; 319
Tanji (10.1016/j.celrep.2022.111523_bib66) 2010; 107
Shin (10.1016/j.celrep.2022.111523_bib61) 2011; 334
Moter (10.1016/j.celrep.2022.111523_bib48) 2000; 41
Chen (10.1016/j.celrep.2022.111523_bib13) 2019; 25
Guo (10.1016/j.celrep.2022.111523_bib26) 2022; 29
Stecher (10.1016/j.celrep.2022.111523_bib64) 2011; 14
Nyholm (10.1016/j.celrep.2022.111523_bib50) 2012; 10
Wang (10.1016/j.celrep.2022.111523_bib70) 2011; 110
Livak (10.1016/j.celrep.2022.111523_bib40) 2001; 25
Broderick (10.1016/j.celrep.2022.111523_bib5) 2014; 5
Engel (10.1016/j.celrep.2022.111523_bib22) 2013; 37
Dillon (10.1016/j.celrep.2022.111523_bib19) 2004; 49
Ceja-Navarro (10.1016/j.celrep.2022.111523_bib11) 2015; 6
Liehl (10.1016/j.celrep.2022.111523_bib39) 2006; 2
Singh (10.1016/j.celrep.2022.111523_bib62) 2016; 9
Neyen (10.1016/j.celrep.2022.111523_bib49) 2012; 189
Thong-On (10.1016/j.celrep.2022.111523_bib67) 2012; 27
Bosco-Drayon (10.1016/j.celrep.2022.111523_bib3) 2012; 12
Marianes (10.1016/j.celrep.2022.111523_bib41) 2013; 2
Pais (10.1016/j.celrep.2022.111523_bib32) 2018; 16
Buchon (10.1016/j.celrep.2022.111523_bib6) 2013; 11
Buchon (10.1016/j.celrep.2022.111523_bib7) 2013; 3
Mellroth (10.1016/j.celrep.2022.111523_bib46) 2003; 278
Saha (10.1016/j.celrep.2022.111523_bib59) 2010; 8
Zaidman-Rémy (10.1016/j.celrep.2022.111523_bib74) 2011; 6
References_xml – volume: 3
  start-page: 1725
  year: 2013
  end-page: 1738
  ident: bib7
  article-title: Morphological and molecular characterization of adult midgut compartmentalization in
  publication-title: Cell Rep.
– volume: 178
  start-page: 901
  year: 2019
  end-page: 918.e16
  ident: bib30
  article-title: Sex differences in intestinal carbohydrate metabolism promote food intake and sperm maturation
  publication-title: Cell
– volume: 189
  start-page: 1886
  year: 2012
  end-page: 1897
  ident: bib49
  article-title: Tissue- and ligand-specific sensing of gram-negative infection in
  publication-title: J. Immunol.
– volume: 27
  start-page: 362
  year: 2018
  end-page: 377.e8
  ident: bib65
  article-title: perpetuates nutritional mutualism by promoting the fitness of its intestinal symbiont
  publication-title: Cell Metabol.
– volume: 27
  start-page: 186
  year: 2012
  end-page: 192
  ident: bib67
  article-title: Isolation and characterization of anaerobic bacteria for symbiotic recycling of uric acid nitrogen in the gut of various termites
  publication-title: Microb. Environ.
– volume: 75
  start-page: 1961
  year: 2009
  end-page: 1969
  ident: bib45
  article-title: Establishment of an analytical system for the human fecal microbiota, based on reverse transcription-quantitative PCR targeting of multicopy rRNA molecules
  publication-title: Appl. Environ. Microbiol.
– volume: 110
  start-page: 1390
  year: 2011
  end-page: 1401
  ident: bib70
  article-title: Comparison of the diversity of the bacterial communities in the intestinal tract of adult
  publication-title: J. Appl. Microbiol.
– volume: 23
  start-page: 215
  year: 2018
  end-page: 228.e4
  ident: bib12
  article-title: Cytosolic and secreted peptidoglycan-degrading enzymes in
  publication-title: Cell Host Microbe
– volume: 29
  start-page: 644
  year: 2011
  end-page: 652
  ident: bib24
  article-title: Full-length transcriptome assembly from RNA-Seq data without a reference genome
  publication-title: Nat. Biotechnol.
– volume: 1
  start-page: 16023
  year: 2016
  ident: bib53
  article-title: Mosquito C-type lectins maintain gut microbiome homeostasis
  publication-title: Nat. Microbiol.
– volume: 156
  start-page: 109
  year: 2013
  end-page: 122
  ident: bib25
  article-title: PGRP-SC2 promotes gut immune homeostasis to limit commensal dysbiosis and extend lifespan
  publication-title: Cell
– volume: 85
  start-page: 018644-18
  year: 2018
  end-page: 18
  ident: bib4
  article-title: The intestinal microbiota of
  publication-title: Appl. Environ. Microbiol.
– volume: 70
  start-page: 3575
  year: 2004
  end-page: 3581
  ident: bib1
  article-title: Characterization of bacterial communities in feces from healthy elderly volunteers and hospitalized elderly patients by using real-time PCR and effects of antibiotic treatment on the fecal microbiota
  publication-title: Appl. Environ. Microbiol.
– volume: 6
  start-page: ra61
  year: 2013
  ident: bib60
  article-title: Transglutaminase-catalyzed protein-protein cross-linking suppresses the activity of the NF-κB-like transcription factor relish
  publication-title: Sci. Signal.
– volume: 334
  start-page: 670
  year: 2011
  end-page: 674
  ident: bib61
  article-title: microbiome modulates host developmental and metabolic homeostasis via insulin signaling
  publication-title: Science
– volume: 11
  start-page: 24
  year: 2018
  ident: bib23
  article-title: Transcriptome analysis of the digestive system of a wood-feeding termite (
  publication-title: Biotechnol. Biofuels
– volume: 70
  start-page: 80
  year: 2014
  end-page: 87
  ident: bib69
  article-title: Identification of cultivable bacteria in the intestinal tract of
  publication-title: Pest Manag. Sci.
– volume: 16
  start-page: e1008441
  year: 2020
  ident: bib55
  article-title: Gut microbiota promotes host resistance to low-temperature stress by stimulating its arginine and proline metabolism pathway in adult
  publication-title: PLoS Pathog.
– volume: 8
  start-page: 15186
  year: 2017
  ident: bib68
  article-title: The digestive and defensive basis of carcass utilization by the burying beetle and its microbiota
  publication-title: Nat. Commun.
– volume: 153
  start-page: 797
  year: 2013
  end-page: 811
  ident: bib33
  article-title: Bacterial-derived uracil as a modulator of mucosal immunity and gut-microbe homeostasis in
  publication-title: Cell
– volume: 10
  start-page: 815
  year: 2012
  end-page: 827
  ident: bib50
  article-title: Knowing your friends: invertebrate innate immunity fosters beneficial bacterial symbioses
  publication-title: Nat. Rev. Microbiol.
– volume: 319
  start-page: 777
  year: 2008
  end-page: 782
  ident: bib58
  article-title: Innate immune homeostasis by the homeobox gene caudal and commensal-gut mutualism in
  publication-title: Science
– volume: 25
  start-page: 697
  year: 2007
  end-page: 743
  ident: bib34
  article-title: The host defense of
  publication-title: Annu. Rev. Immunol.
– volume: 2
  start-page: 17020
  year: 2017
  ident: bib71
  article-title: A Mesh-Duox pathway regulates homeostasis in the insect gut
  publication-title: Nat. Microbiol.
– volume: 6
  start-page: e17231
  year: 2011
  ident: bib74
  article-title: immunity: analysis of PGRP-SB1 expression, enzymatic activity and function
  publication-title: PLoS One
– volume: 25
  start-page: 537
  year: 2019
  end-page: 552.e8
  ident: bib13
  article-title: histone demethylase KDM5 regulates social behavior through immune control and gut microbiota maintenance
  publication-title: Cell Host Microbe
– volume: 35
  start-page: 770
  year: 2011
  end-page: 779
  ident: bib54
  article-title: Negative regulation by amidase PGRPs shapes the
  publication-title: Immunity
– volume: 6
  start-page: e1001097
  year: 2010
  ident: bib21
  article-title: The microbiota mediates pathogen clearance from the gut lumen after non-typhoidal
  publication-title: PLoS Pathog.
– volume: 17
  start-page: 10
  year: 2011
  end-page: 12
  ident: bib43
  article-title: Cutadapt removes adapter sequences from high-throughput sequencing reads
  publication-title: EMBnet. j.
– volume: 114
  start-page: 560
  year: 2021
  end-page: 570
  ident: bib76
  article-title: Manipulation of gut symbionts for improving the sterile insect technique: quality parameters of
  publication-title: J. Econ. Entomol.
– volume: 9
  start-page: 313
  year: 2009
  end-page: 323
  ident: bib57
  article-title: The gut microbiota shapes intestinal immune responses during health and disease
  publication-title: Nat. Rev. Immunol.
– volume: 31
  start-page: 2220
  year: 2021
  end-page: 2226.e4
  ident: bib56
  article-title: Rectal bacteria produce sex pheromones in the male oriental fruit fly
  publication-title: Curr. Biol.
– volume: 114
  start-page: 4775
  year: 2017
  end-page: 4780
  ident: bib77
  article-title: Honeybee gut microbiota promotes host weight gain via bacterial metabolism and hormonal signaling
  publication-title: Proc. Natl. Acad. Sci. USA
– volume: 15
  start-page: 410
  year: 2014
  ident: bib18
  article-title: Corset: enabling differential gene expression analysis for de novo assembled transcriptomes
  publication-title: Genome Biol.
– volume: 12
  start-page: 323
  year: 2011
  ident: bib35
  article-title: RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
  publication-title: BMC Bioinf.
– volume: 29
  start-page: 1145
  year: 2022
  end-page: 1158
  ident: bib26
  article-title: Gut fungal community and its probiotic effect on
  publication-title: Insect Sci.
– volume: 49
  start-page: 71
  year: 2004
  end-page: 92
  ident: bib19
  article-title: The gut bacteria of insects: nonpathogenic interactions
  publication-title: Annu. Rev. Entomol.
– volume: 16
  start-page: e2005710
  year: 2018
  ident: bib32
  article-title: establishes a species-specific mutualistic interaction with stable gut-colonizing bacteria
  publication-title: PLoS Biol.
– volume: 5
  start-page: e011177-14
  year: 2014
  ident: bib5
  article-title: Microbiota-induced changes in
  publication-title: mBio
– volume: 8
  start-page: e44341
  year: 2019
  ident: bib27
  article-title: Synergy and remarkable specificity of antimicrobial peptides in vivo using a systematic knockout approach
  publication-title: Elife
– volume: 11
  start-page: 152
  year: 2022
  ident: bib75
  article-title: The negative regulative roles of
  publication-title: Cells
– volume: 37
  start-page: 699
  year: 2013
  end-page: 735
  ident: bib22
  article-title: The gut microbiota of insects-diversity in structure and function
  publication-title: FEMS Microbiol. Rev.
– volume: 8
  start-page: 147
  year: 2010
  end-page: 162
  ident: bib59
  article-title: Peptidoglycan recognition proteins protect mice from experimental colitis by promoting normal gut flora and preventing induction of interferon-γ
  publication-title: Cell Host Microbe
– volume: 41
  start-page: 85
  year: 2000
  end-page: 112
  ident: bib48
  article-title: Fluorescence in situ hybridization (FISH) for direct visualization of microorganisms
  publication-title: J. Microbiol. Methods
– volume: 6
  start-page: e17788
  year: 2011
  ident: bib38
  article-title: RNA interference of four genes in adult
  publication-title: PLoS One
– volume: 24
  start-page: 463
  year: 2006
  end-page: 473
  ident: bib73
  article-title: The
  publication-title: Immunity
– volume: 12
  start-page: 1656
  year: 2015
  end-page: 1667
  ident: bib17
  article-title: Distinct shifts in microbiota composition during
  publication-title: Cell Rep.
– volume: 109
  start-page: E23
  year: 2012
  end-page: E31
  ident: bib52
  article-title: Wolbachia induces reactive oxygen species (ROS)-dependent activation of the Toll pathway to control dengue virus in the mosquito
  publication-title: Proc. Natl. Acad. Sci. USA
– volume: 30
  start-page: 4432
  year: 2020
  end-page: 4440.e4
  ident: bib37
  article-title: Egg-surface bacteria are indirectly associated with oviposition aversion in
  publication-title: Curr. Biol.
– volume: 278
  start-page: 7059
  year: 2003
  end-page: 7064
  ident: bib46
  article-title: A scavenger function for a
  publication-title: J. Biol. Chem.
– volume: 220
  start-page: iyab188
  year: 2022
  ident: bib8
  article-title: Cecropins contribute to
  publication-title: Genetics
– volume: 279
  start-page: 21121
  year: 2004
  end-page: 21127
  ident: bib28
  article-title: Differential activation of the NF-kappaB-like factors Relish and Dif in
  publication-title: J. Biol. Chem.
– volume: 8
  start-page: 801
  year: 2017
  ident: bib63
  article-title: Spatial structure of the mormon cricket gut microbiome and its predicted contribution to nutrition and immune function
  publication-title: Front. Microbiol.
– volume: 2
  start-page: e14
  year: 2006
  ident: bib2
  article-title: Downregulation of the
  publication-title: PLoS Pathog.
– volume: 85
  start-page: e00803-19
  year: 2019
  end-page: e00819
  ident: bib29
  article-title: Microbial communities in different developmental stages of the oriental fruit fly,
  publication-title: Appl. Environ. Microbiol.
– volume: 65
  start-page: 293
  year: 2020
  end-page: 311
  ident: bib78
  article-title: Mechanisms, applications, and challenges of insect RNA interference
  publication-title: Annu. Rev. Entomol.
– volume: 19
  start-page: 240
  year: 2016
  end-page: 253
  ident: bib36
  article-title: Preventing age-related decline of gut compartmentalization limits microbiota dysbiosis and extends lifespan
  publication-title: Cell Host Microbe
– volume: 2
  start-page: e00886
  year: 2013
  ident: bib41
  article-title: Physiological and stem cell compartmentalization within the
  publication-title: Elife
– volume: 25
  start-page: 402
  year: 2001
  end-page: 408
  ident: bib40
  article-title: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
  publication-title: Methods
– volume: 12
  start-page: 153
  year: 2012
  end-page: 165
  ident: bib3
  article-title: Peptidoglycan sensing by the receptor PGRP-LE in the
  publication-title: Cell Host Microbe
– volume: 50
  start-page: 293
  year: 2005
  end-page: 319
  ident: bib16
  article-title: Invasive phytophagous pests arising through a recent tropical evolutionary radiation: the
  publication-title: Annu. Rev. Entomol.
– volume: 12
  start-page: e0082421
  year: 2021
  ident: bib42
  article-title: antimicrobial peptides and lysozymes regulate gut microbiota composition and abundance
  publication-title: mBio
– volume: 9
  start-page: 127
  year: 2016
  end-page: 135
  ident: bib62
  article-title: Optical scatter patterns facilitate rapid differentiation of Enterobacteriaceae on CHROMagar™ Orientation medium
  publication-title: Microb. Biotechnol.
– volume: 14
  start-page: 82
  year: 2011
  end-page: 91
  ident: bib64
  article-title: Mechanisms controlling pathogen colonization of the gut
  publication-title: Curr. Opin. Microbiol.
– volume: 5
  start-page: 13
  year: 2017
  ident: bib15
  article-title: Gut symbiont enhances insecticide resistance in a significant pest, the oriental fruit fly
  publication-title: Microbiome
– volume: 38
  start-page: 155
  year: 2008
  end-page: 165
  ident: bib14
  article-title: Female-specific doublesex dsRNA interrupts yolk protein gene expression and reproductive ability in oriental fruit fly,
  publication-title: Insect Biochem. Mol. Biol.
– volume: 6
  start-page: 7618
  year: 2015
  ident: bib11
  article-title: Gut microbiota mediate caffeine detoxification in the primary insect pest of coffee
  publication-title: Nat. Commun.
– volume: 2
  start-page: e56
  year: 2006
  ident: bib39
  article-title: Prevalence of local immune response against oral infection in a
  publication-title: PLoS Pathog.
– volume: 78
  start-page: 2830
  year: 2012
  end-page: 2840
  ident: bib44
  article-title: Establishment of characteristic gut bacteria during development of the honeybee worker
  publication-title: Appl. Environ. Microbiol.
– volume: 49
  start-page: 929
  year: 2018
  end-page: 942.e5
  ident: bib31
  article-title: Microbiota-derived lactate activates production of reactive oxygen species by the intestinal NADPH oxidase Nox and shortens
  publication-title: Immunity
– volume: 350
  start-page: 994
  year: 2006
  end-page: 999
  ident: bib47
  article-title: PGRP-SB
  publication-title: Biochem. Biophys. Res. Commun.
– volume: 10
  start-page: 1037
  year: 2016
  end-page: 1050
  ident: bib72
  article-title: The dual oxidase gene
  publication-title: ISME J.
– volume: 11
  start-page: 615
  year: 2013
  end-page: 626
  ident: bib6
  article-title: Gut homeostasis in a microbial world: insights from
  publication-title: Nat. Rev. Microbiol.
– volume: 14
  start-page: 20
  year: 2016
  end-page: 32
  ident: bib20
  article-title: Gut biogeography of the bacterial microbiota
  publication-title: Nat. Rev. Microbiol.
– volume: 11
  start-page: 1946
  year: 2018
  end-page: 1963
  ident: bib9
  article-title: Intestinal probiotics restore the ecological fitness decline of
  publication-title: Evol. Appl.
– volume: 8
  start-page: 6
  year: 2014
  end-page: 18
  ident: bib10
  article-title: Compartmentalized microbial composition, oxygen gradients and nitrogen fixation in the gut of
  publication-title: ISME J.
– volume: 107
  start-page: 14715
  year: 2010
  end-page: 14720
  ident: bib66
  article-title: Heterodimers of NF-kappaB transcription factors DIF and Relish regulate antimicrobial peptide genes in
  publication-title: Proc. Natl. Acad. Sci. USA
– volume: 109
  start-page: E23
  year: 2012
  ident: 10.1016/j.celrep.2022.111523_bib52
  article-title: Wolbachia induces reactive oxygen species (ROS)-dependent activation of the Toll pathway to control dengue virus in the mosquito Aedes aegypti
  publication-title: Proc. Natl. Acad. Sci. USA
  doi: 10.1073/pnas.1116932108
– volume: 9
  start-page: 313
  year: 2009
  ident: 10.1016/j.celrep.2022.111523_bib57
  article-title: The gut microbiota shapes intestinal immune responses during health and disease
  publication-title: Nat. Rev. Immunol.
  doi: 10.1038/nri2515
– volume: 12
  start-page: 1656
  year: 2015
  ident: 10.1016/j.celrep.2022.111523_bib17
  article-title: Distinct shifts in microbiota composition during Drosophila aging impair intestinal function and drive mortality
  publication-title: Cell Rep.
  doi: 10.1016/j.celrep.2015.08.004
– volume: 8
  start-page: 801
  year: 2017
  ident: 10.1016/j.celrep.2022.111523_bib63
  article-title: Spatial structure of the mormon cricket gut microbiome and its predicted contribution to nutrition and immune function
  publication-title: Front. Microbiol.
  doi: 10.3389/fmicb.2017.00801
– volume: 6
  start-page: 7618
  year: 2015
  ident: 10.1016/j.celrep.2022.111523_bib11
  article-title: Gut microbiota mediate caffeine detoxification in the primary insect pest of coffee
  publication-title: Nat. Commun.
  doi: 10.1038/ncomms8618
– volume: 29
  start-page: 1145
  year: 2022
  ident: 10.1016/j.celrep.2022.111523_bib26
  article-title: Gut fungal community and its probiotic effect on Bactrocera dorsalis
  publication-title: Insect Sci.
  doi: 10.1111/1744-7917.12986
– volume: 14
  start-page: 82
  year: 2011
  ident: 10.1016/j.celrep.2022.111523_bib64
  article-title: Mechanisms controlling pathogen colonization of the gut
  publication-title: Curr. Opin. Microbiol.
  doi: 10.1016/j.mib.2010.10.003
– volume: 278
  start-page: 7059
  year: 2003
  ident: 10.1016/j.celrep.2022.111523_bib46
  article-title: A scavenger function for a Drosophila peptidoglycan recognition protein
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M208900200
– volume: 85
  start-page: 018644-18
  year: 2018
  ident: 10.1016/j.celrep.2022.111523_bib4
  article-title: The intestinal microbiota of Hermetia illucens larvae is affected by diet and shows a diverse composition in the different midgut regions
  publication-title: Appl. Environ. Microbiol.
– volume: 279
  start-page: 21121
  year: 2004
  ident: 10.1016/j.celrep.2022.111523_bib28
  article-title: Differential activation of the NF-kappaB-like factors Relish and Dif in Drosophila melanogaster by fungi and Gram-positive bacteria
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M313856200
– volume: 8
  start-page: 15186
  year: 2017
  ident: 10.1016/j.celrep.2022.111523_bib68
  article-title: The digestive and defensive basis of carcass utilization by the burying beetle and its microbiota
  publication-title: Nat. Commun.
  doi: 10.1038/ncomms15186
– volume: 10
  start-page: 1037
  year: 2016
  ident: 10.1016/j.celrep.2022.111523_bib72
  article-title: The dual oxidase gene BdDuox regulates the intestinal bacterial community homeostasis of Bactrocera dorsalis
  publication-title: ISME J.
  doi: 10.1038/ismej.2015.202
– volume: 114
  start-page: 4775
  year: 2017
  ident: 10.1016/j.celrep.2022.111523_bib77
  article-title: Honeybee gut microbiota promotes host weight gain via bacterial metabolism and hormonal signaling
  publication-title: Proc. Natl. Acad. Sci. USA
  doi: 10.1073/pnas.1701819114
– volume: 8
  start-page: 6
  year: 2014
  ident: 10.1016/j.celrep.2022.111523_bib10
  article-title: Compartmentalized microbial composition, oxygen gradients and nitrogen fixation in the gut of Odontotaenius disjunctus
  publication-title: ISME J.
  doi: 10.1038/ismej.2013.134
– volume: 6
  start-page: e1001097
  year: 2010
  ident: 10.1016/j.celrep.2022.111523_bib21
  article-title: The microbiota mediates pathogen clearance from the gut lumen after non-typhoidal Salmonella diarrhea
  publication-title: PLoS Pathog.
  doi: 10.1371/journal.ppat.1001097
– volume: 35
  start-page: 770
  year: 2011
  ident: 10.1016/j.celrep.2022.111523_bib54
  article-title: Negative regulation by amidase PGRPs shapes the Drosophila antibacterial response and protects the fly from innocuous infection
  publication-title: Immunity
  doi: 10.1016/j.immuni.2011.09.018
– volume: 31
  start-page: 2220
  year: 2021
  ident: 10.1016/j.celrep.2022.111523_bib56
  article-title: Rectal bacteria produce sex pheromones in the male oriental fruit fly
  publication-title: Curr. Biol.
  doi: 10.1016/j.cub.2021.02.046
– volume: 38
  start-page: 155
  year: 2008
  ident: 10.1016/j.celrep.2022.111523_bib14
  article-title: Female-specific doublesex dsRNA interrupts yolk protein gene expression and reproductive ability in oriental fruit fly, Bactrocera dorsalis (Hendel)
  publication-title: Insect Biochem. Mol. Biol.
  doi: 10.1016/j.ibmb.2007.10.003
– volume: 29
  start-page: 644
  year: 2011
  ident: 10.1016/j.celrep.2022.111523_bib24
  article-title: Full-length transcriptome assembly from RNA-Seq data without a reference genome
  publication-title: Nat. Biotechnol.
  doi: 10.1038/nbt.1883
– volume: 24
  start-page: 463
  year: 2006
  ident: 10.1016/j.celrep.2022.111523_bib73
  article-title: The Drosophila amidase PGRP-LB modulates the immune response to bacterial infection
  publication-title: Immunity
  doi: 10.1016/j.immuni.2006.02.012
– volume: 27
  start-page: 186
  year: 2012
  ident: 10.1016/j.celrep.2022.111523_bib67
  article-title: Isolation and characterization of anaerobic bacteria for symbiotic recycling of uric acid nitrogen in the gut of various termites
  publication-title: Microb. Environ.
  doi: 10.1264/jsme2.ME11325
– volume: 23
  start-page: 215
  year: 2018
  ident: 10.1016/j.celrep.2022.111523_bib12
  article-title: Cytosolic and secreted peptidoglycan-degrading enzymes in Drosophila respectively control local and systemic immune responses to microbiota
  publication-title: Cell Host Microbe
  doi: 10.1016/j.chom.2017.12.007
– volume: 350
  start-page: 994
  year: 2006
  ident: 10.1016/j.celrep.2022.111523_bib47
  article-title: PGRP-SB1: an N-acetylmuramoyl L-alanine amidase with antibacterial activity
  publication-title: Biochem. Biophys. Res. Commun.
  doi: 10.1016/j.bbrc.2006.09.139
– volume: 15
  start-page: 410
  year: 2014
  ident: 10.1016/j.celrep.2022.111523_bib18
  article-title: Corset: enabling differential gene expression analysis for de novo assembled transcriptomes
  publication-title: Genome Biol.
– volume: 11
  start-page: 1946
  year: 2018
  ident: 10.1016/j.celrep.2022.111523_bib9
  article-title: Intestinal probiotics restore the ecological fitness decline of Bactrocera dorsalis by irradiation
  publication-title: Evol. Appl.
  doi: 10.1111/eva.12698
– volume: 178
  start-page: 901
  year: 2019
  ident: 10.1016/j.celrep.2022.111523_bib30
  article-title: Sex differences in intestinal carbohydrate metabolism promote food intake and sperm maturation
  publication-title: Cell
  doi: 10.1016/j.cell.2019.07.029
– volume: 10
  start-page: 815
  year: 2012
  ident: 10.1016/j.celrep.2022.111523_bib50
  article-title: Knowing your friends: invertebrate innate immunity fosters beneficial bacterial symbioses
  publication-title: Nat. Rev. Microbiol.
  doi: 10.1038/nrmicro2894
– volume: 6
  start-page: e17231
  year: 2011
  ident: 10.1016/j.celrep.2022.111523_bib74
  article-title: Drosophila immunity: analysis of PGRP-SB1 expression, enzymatic activity and function
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0017231
– volume: 12
  start-page: e0082421
  year: 2021
  ident: 10.1016/j.celrep.2022.111523_bib42
  article-title: Drosophila antimicrobial peptides and lysozymes regulate gut microbiota composition and abundance
  publication-title: mBio
  doi: 10.1128/mBio.00824-21
– volume: 49
  start-page: 71
  year: 2004
  ident: 10.1016/j.celrep.2022.111523_bib19
  article-title: The gut bacteria of insects: nonpathogenic interactions
  publication-title: Annu. Rev. Entomol.
  doi: 10.1146/annurev.ento.49.061802.123416
– volume: 14
  start-page: 20
  year: 2016
  ident: 10.1016/j.celrep.2022.111523_bib20
  article-title: Gut biogeography of the bacterial microbiota
  publication-title: Nat. Rev. Microbiol.
  doi: 10.1038/nrmicro3552
– volume: 27
  start-page: 362
  year: 2018
  ident: 10.1016/j.celrep.2022.111523_bib65
  article-title: Drosophila perpetuates nutritional mutualism by promoting the fitness of its intestinal symbiont Lactobacillus plantarum
  publication-title: Cell Metabol.
  doi: 10.1016/j.cmet.2017.11.011
– volume: 3
  start-page: 1725
  year: 2013
  ident: 10.1016/j.celrep.2022.111523_bib7
  article-title: Morphological and molecular characterization of adult midgut compartmentalization in Drosophila
  publication-title: Cell Rep.
  doi: 10.1016/j.celrep.2013.04.001
– volume: 50
  start-page: 293
  year: 2005
  ident: 10.1016/j.celrep.2022.111523_bib16
  article-title: Invasive phytophagous pests arising through a recent tropical evolutionary radiation: the Bactrocera dorsalis complex of fruit flies
  publication-title: Annu. Rev. Entomol.
  doi: 10.1146/annurev.ento.50.071803.130428
– volume: 107
  start-page: 14715
  year: 2010
  ident: 10.1016/j.celrep.2022.111523_bib66
  article-title: Heterodimers of NF-kappaB transcription factors DIF and Relish regulate antimicrobial peptide genes in Drosophila
  publication-title: Proc. Natl. Acad. Sci. USA
  doi: 10.1073/pnas.1009473107
– volume: 11
  start-page: 152
  year: 2022
  ident: 10.1016/j.celrep.2022.111523_bib75
  article-title: The negative regulative roles of BdPGRPs in the Imd signaling pathway of Bactrocera dorsalis
  publication-title: Cells
  doi: 10.3390/cells11010152
– volume: 25
  start-page: 402
  year: 2001
  ident: 10.1016/j.celrep.2022.111523_bib40
  article-title: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
  publication-title: Methods
  doi: 10.1006/meth.2001.1262
– volume: 334
  start-page: 670
  year: 2011
  ident: 10.1016/j.celrep.2022.111523_bib61
  article-title: Drosophila microbiome modulates host developmental and metabolic homeostasis via insulin signaling
  publication-title: Science
  doi: 10.1126/science.1212782
– volume: 12
  start-page: 323
  year: 2011
  ident: 10.1016/j.celrep.2022.111523_bib35
  article-title: RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
  publication-title: BMC Bioinf.
  doi: 10.1186/1471-2105-12-323
– volume: 189
  start-page: 1886
  year: 2012
  ident: 10.1016/j.celrep.2022.111523_bib49
  article-title: Tissue- and ligand-specific sensing of gram-negative infection in Drosophila by PGRP-LC isoforms and PGRP-LE
  publication-title: J. Immunol.
  doi: 10.4049/jimmunol.1201022
– volume: 2
  start-page: e00886
  year: 2013
  ident: 10.1016/j.celrep.2022.111523_bib41
  article-title: Physiological and stem cell compartmentalization within the Drosophila midgut
  publication-title: Elife
  doi: 10.7554/eLife.00886
– volume: 153
  start-page: 797
  year: 2013
  ident: 10.1016/j.celrep.2022.111523_bib33
  article-title: Bacterial-derived uracil as a modulator of mucosal immunity and gut-microbe homeostasis in
  publication-title: Cell
  doi: 10.1016/j.cell.2013.04.009
– volume: 25
  start-page: 537
  year: 2019
  ident: 10.1016/j.celrep.2022.111523_bib13
  article-title: Drosophila histone demethylase KDM5 regulates social behavior through immune control and gut microbiota maintenance
  publication-title: Cell Host Microbe
  doi: 10.1016/j.chom.2019.02.003
– volume: 8
  start-page: e44341
  year: 2019
  ident: 10.1016/j.celrep.2022.111523_bib27
  article-title: Synergy and remarkable specificity of antimicrobial peptides in vivo using a systematic knockout approach
  publication-title: Elife
  doi: 10.7554/eLife.44341
– volume: 41
  start-page: 85
  year: 2000
  ident: 10.1016/j.celrep.2022.111523_bib48
  article-title: Fluorescence in situ hybridization (FISH) for direct visualization of microorganisms
  publication-title: J. Microbiol. Methods
  doi: 10.1016/S0167-7012(00)00152-4
– volume: 75
  start-page: 1961
  year: 2009
  ident: 10.1016/j.celrep.2022.111523_bib45
  article-title: Establishment of an analytical system for the human fecal microbiota, based on reverse transcription-quantitative PCR targeting of multicopy rRNA molecules
  publication-title: Appl. Environ. Microbiol.
  doi: 10.1128/AEM.01843-08
– volume: 49
  start-page: 929
  year: 2018
  ident: 10.1016/j.celrep.2022.111523_bib31
  article-title: Microbiota-derived lactate activates production of reactive oxygen species by the intestinal NADPH oxidase Nox and shortens Drosophila lifespan
  publication-title: Immunity
  doi: 10.1016/j.immuni.2018.09.017
– volume: 17
  start-page: 10
  year: 2011
  ident: 10.1016/j.celrep.2022.111523_bib43
  article-title: Cutadapt removes adapter sequences from high-throughput sequencing reads
  publication-title: EMBnet. j.
  doi: 10.14806/ej.17.1.200
– volume: 78
  start-page: 2830
  year: 2012
  ident: 10.1016/j.celrep.2022.111523_bib44
  article-title: Establishment of characteristic gut bacteria during development of the honeybee worker
  publication-title: Appl. Environ. Microbiol.
  doi: 10.1128/AEM.07810-11
– volume: 37
  start-page: 699
  year: 2013
  ident: 10.1016/j.celrep.2022.111523_bib22
  article-title: The gut microbiota of insects-diversity in structure and function
  publication-title: FEMS Microbiol. Rev.
  doi: 10.1111/1574-6976.12025
– volume: 110
  start-page: 1390
  year: 2011
  ident: 10.1016/j.celrep.2022.111523_bib70
  article-title: Comparison of the diversity of the bacterial communities in the intestinal tract of adult Bactrocera dorsalis from three different populations
  publication-title: J. Appl. Microbiol.
  doi: 10.1111/j.1365-2672.2011.05001.x
– volume: 2
  start-page: 17020
  year: 2017
  ident: 10.1016/j.celrep.2022.111523_bib71
  article-title: A Mesh-Duox pathway regulates homeostasis in the insect gut
  publication-title: Nat. Microbiol.
  doi: 10.1038/nmicrobiol.2017.20
– volume: 11
  start-page: 24
  year: 2018
  ident: 10.1016/j.celrep.2022.111523_bib23
  article-title: Transcriptome analysis of the digestive system of a wood-feeding termite (Coptotermes formosanus) revealed a unique mechanism for effective biomass degradation
  publication-title: Biotechnol. Biofuels
  doi: 10.1186/s13068-018-1015-1
– volume: 11
  start-page: 615
  year: 2013
  ident: 10.1016/j.celrep.2022.111523_bib6
  article-title: Gut homeostasis in a microbial world: insights from Drosophila melanogaster
  publication-title: Nat. Rev. Microbiol.
  doi: 10.1038/nrmicro3074
– volume: 12
  start-page: 153
  year: 2012
  ident: 10.1016/j.celrep.2022.111523_bib3
  article-title: Peptidoglycan sensing by the receptor PGRP-LE in the Drosophila gut induces immune responses to infectious bacteria and tolerance to microbiota
  publication-title: Cell Host Microbe
  doi: 10.1016/j.chom.2012.06.002
– volume: 156
  start-page: 109
  year: 2013
  ident: 10.1016/j.celrep.2022.111523_bib25
  article-title: PGRP-SC2 promotes gut immune homeostasis to limit commensal dysbiosis and extend lifespan
  publication-title: Cell
  doi: 10.1016/j.cell.2013.12.018
– volume: 70
  start-page: 80
  year: 2014
  ident: 10.1016/j.celrep.2022.111523_bib69
  article-title: Identification of cultivable bacteria in the intestinal tract of Bactrocera dorsalis from three different populations and determination of their attractive potential
  publication-title: Pest Manag. Sci.
  doi: 10.1002/ps.3528
– volume: 16
  start-page: e2005710
  year: 2018
  ident: 10.1016/j.celrep.2022.111523_bib32
  article-title: Drosophila melanogaster establishes a species-specific mutualistic interaction with stable gut-colonizing bacteria
  publication-title: PLoS Biol.
  doi: 10.1371/journal.pbio.2005710
– volume: 319
  start-page: 777
  year: 2008
  ident: 10.1016/j.celrep.2022.111523_bib58
  article-title: Innate immune homeostasis by the homeobox gene caudal and commensal-gut mutualism in Drosophila
  publication-title: Science
  doi: 10.1126/science.1149357
– volume: 25
  start-page: 697
  year: 2007
  ident: 10.1016/j.celrep.2022.111523_bib34
  article-title: The host defense of Drosophila melanogaster
  publication-title: Annu. Rev. Immunol.
  doi: 10.1146/annurev.immunol.25.022106.141615
– volume: 1
  start-page: 16023
  year: 2016
  ident: 10.1016/j.celrep.2022.111523_bib53
  article-title: Mosquito C-type lectins maintain gut microbiome homeostasis
  publication-title: Nat. Microbiol.
  doi: 10.1038/nmicrobiol.2016.23
– volume: 30
  start-page: 4432
  year: 2020
  ident: 10.1016/j.celrep.2022.111523_bib37
  article-title: Egg-surface bacteria are indirectly associated with oviposition aversion in Bactrocera dorsalis
  publication-title: Curr. Biol.
  doi: 10.1016/j.cub.2020.08.080
– volume: 65
  start-page: 293
  year: 2020
  ident: 10.1016/j.celrep.2022.111523_bib78
  article-title: Mechanisms, applications, and challenges of insect RNA interference
  publication-title: Annu. Rev. Entomol.
  doi: 10.1146/annurev-ento-011019-025224
– volume: 9
  start-page: 127
  year: 2016
  ident: 10.1016/j.celrep.2022.111523_bib62
  article-title: Optical scatter patterns facilitate rapid differentiation of Enterobacteriaceae on CHROMagar™ Orientation medium
  publication-title: Microb. Biotechnol.
  doi: 10.1111/1751-7915.12323
– volume: 114
  start-page: 560
  year: 2021
  ident: 10.1016/j.celrep.2022.111523_bib76
  article-title: Manipulation of gut symbionts for improving the sterile insect technique: quality parameters of Bactrocera dorsalis (Diptera: Tephritidae) genetic sexing strain males after feeding on bacteria-enriched diets
  publication-title: J. Econ. Entomol.
  doi: 10.1093/jee/toaa294
– volume: 5
  start-page: e011177-14
  year: 2014
  ident: 10.1016/j.celrep.2022.111523_bib5
  article-title: Microbiota-induced changes in Drosophila melanogaster host gene expression and gut morphology
  publication-title: mBio
  doi: 10.1128/mBio.01117-14
– volume: 5
  start-page: 13
  year: 2017
  ident: 10.1016/j.celrep.2022.111523_bib15
  article-title: Gut symbiont enhances insecticide resistance in a significant pest, the oriental fruit fly Bactrocera dorsalis (Hendel)
  publication-title: Microbiome
  doi: 10.1186/s40168-017-0236-z
– volume: 8
  start-page: 147
  year: 2010
  ident: 10.1016/j.celrep.2022.111523_bib59
  article-title: Peptidoglycan recognition proteins protect mice from experimental colitis by promoting normal gut flora and preventing induction of interferon-γ
  publication-title: Cell Host Microbe
  doi: 10.1016/j.chom.2010.07.005
– volume: 6
  start-page: ra61
  year: 2013
  ident: 10.1016/j.celrep.2022.111523_bib60
  article-title: Transglutaminase-catalyzed protein-protein cross-linking suppresses the activity of the NF-κB-like transcription factor relish
  publication-title: Sci. Signal.
  doi: 10.1126/scisignal.2003970
– volume: 16
  start-page: e1008441
  year: 2020
  ident: 10.1016/j.celrep.2022.111523_bib55
  article-title: Gut microbiota promotes host resistance to low-temperature stress by stimulating its arginine and proline metabolism pathway in adult Bactrocera dorsalis
  publication-title: PLoS Pathog.
  doi: 10.1371/journal.ppat.1008441
– volume: 19
  start-page: 240
  year: 2016
  ident: 10.1016/j.celrep.2022.111523_bib36
  article-title: Preventing age-related decline of gut compartmentalization limits microbiota dysbiosis and extends lifespan
  publication-title: Cell Host Microbe
  doi: 10.1016/j.chom.2016.01.008
– volume: 2
  start-page: e56
  year: 2006
  ident: 10.1016/j.celrep.2022.111523_bib39
  article-title: Prevalence of local immune response against oral infection in a Drosophila/Pseudomonas infection model
  publication-title: PLoS Pathog.
  doi: 10.1371/journal.ppat.0020056
– volume: 70
  start-page: 3575
  year: 2004
  ident: 10.1016/j.celrep.2022.111523_bib1
  article-title: Characterization of bacterial communities in feces from healthy elderly volunteers and hospitalized elderly patients by using real-time PCR and effects of antibiotic treatment on the fecal microbiota
  publication-title: Appl. Environ. Microbiol.
  doi: 10.1128/AEM.70.6.3575-3581.2004
– volume: 2
  start-page: e14
  year: 2006
  ident: 10.1016/j.celrep.2022.111523_bib2
  article-title: Downregulation of the Drosophila immune response by peptidoglycan recognition proteins SC1 and SC2
  publication-title: PLoS Pathog.
  doi: 10.1371/journal.ppat.0020014
– volume: 85
  start-page: e00803-19
  year: 2019
  ident: 10.1016/j.celrep.2022.111523_bib29
  article-title: Microbial communities in different developmental stages of the oriental fruit fly, Bactrocera dorsalis, are associated with differentially expressed peptidoglycan recognition protein-encoding genes
  publication-title: Appl. Environ. Microbiol.
  doi: 10.1128/AEM.00803-19
– volume: 6
  start-page: e17788
  year: 2011
  ident: 10.1016/j.celrep.2022.111523_bib38
  article-title: RNA interference of four genes in adult Bactrocera dorsalis by feeding their dsRNAs
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0017788
– volume: 220
  start-page: iyab188
  year: 2022
  ident: 10.1016/j.celrep.2022.111523_bib8
  article-title: Cecropins contribute to Drosophila host defense against a subset of fungal and Gram-negative bacterial infection
  publication-title: Genetics
  doi: 10.1093/genetics/iyab188
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Snippet All metazoan guts are subject to opposing pressures wherein the immune system must eliminate pathogens while tolerating the presence of symbiotic microbiota....
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SubjectTerms Bactrocera dorsalis
gut microbiota
Imd pathway
immune genes
PGRPs
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Title Compartmentalized PGRP expression along the dipteran Bactrocera dorsalis gut forms a zone of protection for symbiotic bacteria
URI https://dx.doi.org/10.1016/j.celrep.2022.111523
https://www.proquest.com/docview/2726920699
Volume 41
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