Emerging challenges in assessing bio-based nanosystems’ behaviour under in vitro digestion focused on food applications – A critical view and future perspectives

• Published in: Food research international Vol. 157; p. 111417
• Main Authors: Madalena, Daniel, Fernandes, Jean-Michel, Avelar, Zita, Gonçalves, Raquel F.S., Ramos, Óscar L., Vicente, António A., Pinheiro, Ana C.
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.07.2022
• Subjects: Bioaccessibility; bioavailability; digestion; Digestion analysis techniques; digestive tract; food research; Gastrointestinal digestion; Gastrointestinal in vitro model; Limitations of digestion assays; nanotechnology; novel foods; nutrient uptake; Raman spectroscopy; rheology; Validation; X-radiation; Validation; Gastrointestinal digestion; Bioaccessibility; Digestion analysis techniques; Gastrointestinal in vitro model; Limitations of digestion assays

[Display omitted] •Nanosystems’ nature and processing techniques influence its digestion kinetics;•Real-time analytical tools can provide more accurate results;•Efforts must be made towards in vitro digestion models’ standardization;•The validation in vitro digestion models must be addressed. The cu...