Changes in physical activity and adiposity with all-cause, cardiovascular disease, and cancer mortality
Background The relationship between joint changes in physical activity and adiposity with mortality is not well understood. We examined the association of changes in these two established risk factors with all-cause (ACM), cardiovascular disease (CVD), and cancer mortality. Methods We used longitudi...
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Published in | International Journal of Obesity Vol. 46; no. 10; pp. 1849 - 1858 |
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Main Authors | , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
London
Nature Publishing Group UK
01.10.2022
Nature Publishing Group |
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Abstract | Background
The relationship between joint changes in physical activity and adiposity with mortality is not well understood. We examined the association of changes in these two established risk factors with all-cause (ACM), cardiovascular disease (CVD), and cancer mortality.
Methods
We used longitudinal data from Taiwan’s MJ Cohort, comprising 116,228 general population adults recruited from 1998-2013 with repeated measures 4.6 y (2.5) apart and followed up for mortality for 11.9 y (3.5). Physical activity, body mass index (BMI), waist circumference (WC), and body fat percentage (BF%) groups and changes were based on public health and clinical guidelines.
Results
Compared to stable-insufficient physical activity, increasing physical activity from any baseline level was associated with lower ACM (HR [95%CI]): 0.85 [0.74, 0.96]) and CVD mortality (0.72 [0.55, 0.93]) risk. This was approximately equal to meeting physical activity guidelines at both timepoints (eg: 0.71 [0.58, 0.88] for CVD mortality). Compared to stable-overweight/moderate adiposity, decreasing adiposity level attenuated but did not offset mortality risk for all three outcomes (eg: BMI = 0.95 [0.76, 1.16] for CVD mortality). Only maintaining a healthy adiposity level at both timepoints offset mortality risk (BMI = 0.75 [0.61, 0.89]) for CVD mortality). In the joint changes analyses, lower mortality risk was a consequence of increases in physical activity across adiposity change groups (eg: WC decrease = 0.57 [0.48, 0.67]; WC stability = 0.73 [0.66, 0.80], WC increase = 0.83 [0.72, 0.97] for ACM). Decreasing adiposity attenuated the negative associations of decreased physical activity (BF% = 1.13 [0.95, 1.35] for ACM).
Conclusions
We found a lower risk for ACM, CVD, and cancer mortality from increasing physical activity and an attenuation from decreasing adiposity regardless of baseline levels. The beneficial associations of joint changes were primarily driven by physical activity, suggesting lower mortality risk may be more immediate through physical activity improvements compared to adiposity improvements alone. |
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AbstractList | Abstract Background The relationship between joint changes in physical activity and adiposity with mortality is not well understood. We examined the association of changes in these two established risk factors with all-cause (ACM), cardiovascular disease (CVD), and cancer mortality. Methods We used longitudinal data from Taiwan’s MJ Cohort, comprising 116,228 general population adults recruited from 1998-2013 with repeated measures 4.6 y (2.5) apart and followed up for mortality for 11.9 y (3.5). Physical activity, body mass index (BMI), waist circumference (WC), and body fat percentage (BF%) groups and changes were based on public health and clinical guidelines. Results Compared to stable-insufficient physical activity, increasing physical activity from any baseline level was associated with lower ACM (HR [95%CI]): 0.85 [0.74, 0.96]) and CVD mortality (0.72 [0.55, 0.93]) risk. This was approximately equal to meeting physical activity guidelines at both timepoints (eg: 0.71 [0.58, 0.88] for CVD mortality). Compared to stable-overweight/moderate adiposity, decreasing adiposity level attenuated but did not offset mortality risk for all three outcomes (eg: BMI = 0.95 [0.76, 1.16] for CVD mortality). Only maintaining a healthy adiposity level at both timepoints offset mortality risk (BMI = 0.75 [0.61, 0.89]) for CVD mortality). In the joint changes analyses, lower mortality risk was a consequence of increases in physical activity across adiposity change groups (eg: WC decrease = 0.57 [0.48, 0.67]; WC stability = 0.73 [0.66, 0.80], WC increase = 0.83 [0.72, 0.97] for ACM). Decreasing adiposity attenuated the negative associations of decreased physical activity (BF% = 1.13 [0.95, 1.35] for ACM). Conclusions We found a lower risk for ACM, CVD, and cancer mortality from increasing physical activity and an attenuation from decreasing adiposity regardless of baseline levels. The beneficial associations of joint changes were primarily driven by physical activity, suggesting lower mortality risk may be more immediate through physical activity improvements compared to adiposity improvements alone. BACKGROUNDThe relationship between joint changes in physical activity and adiposity with mortality is not well understood. We examined the association of changes in these two established risk factors with all-cause (ACM), cardiovascular disease (CVD), and cancer mortality. METHODSWe used longitudinal data from Taiwan's MJ Cohort, comprising 116,228 general population adults recruited from 1998-2013 with repeated measures 4.6 y (2.5) apart and followed up for mortality for 11.9 y (3.5). Physical activity, body mass index (BMI), waist circumference (WC), and body fat percentage (BF%) groups and changes were based on public health and clinical guidelines. RESULTSCompared to stable-insufficient physical activity, increasing physical activity from any baseline level was associated with lower ACM (HR [95%CI]): 0.85 [0.74, 0.96]) and CVD mortality (0.72 [0.55, 0.93]) risk. This was approximately equal to meeting physical activity guidelines at both timepoints (eg: 0.71 [0.58, 0.88] for CVD mortality). Compared to stable-overweight/moderate adiposity, decreasing adiposity level attenuated but did not offset mortality risk for all three outcomes (eg: BMI = 0.95 [0.76, 1.16] for CVD mortality). Only maintaining a healthy adiposity level at both timepoints offset mortality risk (BMI = 0.75 [0.61, 0.89]) for CVD mortality). In the joint changes analyses, lower mortality risk was a consequence of increases in physical activity across adiposity change groups (eg: WC decrease = 0.57 [0.48, 0.67]; WC stability = 0.73 [0.66, 0.80], WC increase = 0.83 [0.72, 0.97] for ACM). Decreasing adiposity attenuated the negative associations of decreased physical activity (BF% = 1.13 [0.95, 1.35] for ACM). CONCLUSIONSWe found a lower risk for ACM, CVD, and cancer mortality from increasing physical activity and an attenuation from decreasing adiposity regardless of baseline levels. The beneficial associations of joint changes were primarily driven by physical activity, suggesting lower mortality risk may be more immediate through physical activity improvements compared to adiposity improvements alone. Background The relationship between joint changes in physical activity and adiposity with mortality is not well understood. We examined the association of changes in these two established risk factors with all-cause (ACM), cardiovascular disease (CVD), and cancer mortality. Methods We used longitudinal data from Taiwan’s MJ Cohort, comprising 116,228 general population adults recruited from 1998-2013 with repeated measures 4.6 y (2.5) apart and followed up for mortality for 11.9 y (3.5). Physical activity, body mass index (BMI), waist circumference (WC), and body fat percentage (BF%) groups and changes were based on public health and clinical guidelines. Results Compared to stable-insufficient physical activity, increasing physical activity from any baseline level was associated with lower ACM (HR [95%CI]): 0.85 [0.74, 0.96]) and CVD mortality (0.72 [0.55, 0.93]) risk. This was approximately equal to meeting physical activity guidelines at both timepoints (eg: 0.71 [0.58, 0.88] for CVD mortality). Compared to stable-overweight/moderate adiposity, decreasing adiposity level attenuated but did not offset mortality risk for all three outcomes (eg: BMI = 0.95 [0.76, 1.16] for CVD mortality). Only maintaining a healthy adiposity level at both timepoints offset mortality risk (BMI = 0.75 [0.61, 0.89]) for CVD mortality). In the joint changes analyses, lower mortality risk was a consequence of increases in physical activity across adiposity change groups (eg: WC decrease = 0.57 [0.48, 0.67]; WC stability = 0.73 [0.66, 0.80], WC increase = 0.83 [0.72, 0.97] for ACM). Decreasing adiposity attenuated the negative associations of decreased physical activity (BF% = 1.13 [0.95, 1.35] for ACM). Conclusions We found a lower risk for ACM, CVD, and cancer mortality from increasing physical activity and an attenuation from decreasing adiposity regardless of baseline levels. The beneficial associations of joint changes were primarily driven by physical activity, suggesting lower mortality risk may be more immediate through physical activity improvements compared to adiposity improvements alone. |
Author | Hamer, Mark Chen, Li Jung del Pozo Cruz, Borja Lee, I-Min Ahmadi, Matthew N. Lai, Yun-Ju Ku, Po Wen Eroglu, Elif Stamatakis, Emmanuel |
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CitedBy_id | crossref_primary_10_1016_j_sleep_2024_05_003 crossref_primary_10_1007_s10935_024_00782_2 crossref_primary_10_3390_jpm13091326 crossref_primary_10_3390_jcm11195649 crossref_primary_10_17116_profmed20232612152 crossref_primary_10_1016_j_annepidem_2023_11_008 crossref_primary_10_1136_bjsports_2023_107007 crossref_primary_10_34133_research_0214 crossref_primary_10_1158_2767_9764_CRC_23_0570 crossref_primary_10_1038_s41366_022_01209_w crossref_primary_10_1186_s12872_024_03817_y crossref_primary_10_3390_nu14245279 |
Cites_doi | 10.1016/j.jacc.2016.06.067 10.1016/S0140-6736(13)61836-X 10.1016/S1470-2045(10)70141-8 10.1136/bmj.j4849 10.1249/MSS.0b013e31821ece12 10.1038/sj.ijo.0802870 10.1016/j.jacc.2018.08.2141 10.1136/bmjopen-2020-039239 10.1093/gerona/56.suppl_2.13 10.1152/physrev.00012.2011 10.1002/ijc.32148 10.1152/physrev.00033.2011 10.1001/jama.2018.14854 10.1093/eurheartj/ehy339 10.1158/1055-9965.EPI-15-0578 10.1016/j.jacc.2013.11.003 10.1016/j.jacc.2019.03.010 10.1097/EDE.0b013e3181b5f520 10.1136/bmj.f5446 10.1161/CIRCULATIONAHA.109.192644 10.1016/j.amjmed.2017.01.043 10.1016/j.arcmed.2015.06.006 10.1001/jamanetworkopen.2019.0355 10.1161/CIRCULATIONAHA.108.790048 10.1249/JSR.0000000000000623 10.1139/h05-038 10.1007/s13668-014-0099-x 10.1056/NEJMra1514009 10.1016/j.mayocp.2020.06.049 10.3322/caac.21492 10.1016/S0140-6736(97)12355-8 10.1016/j.ehj.2004.10.020 10.1038/ijo.2009.274 10.1001/jama.2018.21554 10.1371/journal.pmed.1001335 10.1136/bjsports-2020-102955 10.1093/eurheartj/ehab484 10.1016/j.jacc.2018.01.011 10.1186/s12966-019-0809-2 10.1093/oxfordjournals.aje.a010013 10.1111/j.1365-2796.2008.01985.x 10.1161/CIRCRESAHA.118.312669 10.1177/174182670301000210 10.1097/EDE.0000000000000864 10.1249/MSS.0b013e3182a0595f 10.1080/01621459.1999.10474144 10.1093/ije/dyy272 10.1161/CIRCULATIONAHA.107.729939 10.1016/j.jacc.2018.08.1037 10.1093/aje/kwp053 10.1056/NEJMoa042135 10.1177/0898264309350076 10.1136/bmj.l2323 10.1007/s10654-010-9497-6 10.1093/ije/dyw282 10.1016/S2214-109X(18)30357-7 10.1111/j.1467-789X.2011.00879.x 10.1016/j.mayocp.2021.11.026 10.1136/jech-2017-208895 10.1136/bmj.l5584 10.1016/bs.afnr.2015.07.001 10.1007/s40273-014-0243-x |
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References | Bray, Ferlay, Soerjomataram, Siegel, Torre, Jemal (CR20) 2018; 68 Piercy, Troiano, Ballard, Carlson, Fulton, Galuska (CR17) 2018; 320 Ainsworth, Haskell, Herrmann, Meckes, Bassett, Tudor-Locke (CR26) 2011; 43 Hu, Tuomilehto, Silventoinen, Barengo, Peltonen, Jousilahti (CR61) 2005; 29 Moore, Patel, Matthews, Berrington de Gonzalez, Park, Katki (CR3) 2012; 9 Mora, Cook, Buring, Ridker, Lee (CR43) 2007; 116 Visseren, Mach, Smulders, Carballo, Koskinas, Bäck (CR21) 2021; 42 CR39 CR38 CR37 Hamer, Bauman, Bell, Stamatakis (CR36) 2019; 48 Czernichow, Kengne, Stamatakis, Hamer, Batty (CR67) 2011; 12 Ma, Avenell, Bolland, Hudson, Stewart, Robertson (CR58) 2017; 359 CR31 Katzmarzyk, Craig (CR7) 2006; 31 Clarke, Shipley, Lewington, Youngman, Collins, Marmot (CR11) 1999; 150 Williams, Mancia, Spiering, Agabiti Rosei, Azizi, Burnier (CR25) 2018; 39 Haneuse, VanderWeele, Arterburn (CR34) 2019; 321 Moholdt, Lavie, Nauman (CR16) 2017; 130 Pang, Kartsonaki, Guo, Chen, Yang, Bian (CR52) 2019; 145 Pi-Sunyer (CR59) 2014; 3 Alberti, Eckel, Grundy, Zimmet, Cleeman, Donato (CR32) 2009; 120 Mathur, Ding, Riddell, VanderWeele (CR35) 2018; 29 Barquera, Pedroza-Tobías, Medina, Hernández-Barrera, Bibbins-Domingo, Lozano (CR40) 2015; 46 Torre, Siegel, Ward, Jemal (CR41) 2016; 25 Parr, Batty, Lam, Barzi, Fang, Ho (CR49) 2010; 11 Tchernof, Després (CR65) 2013; 93 Nordstoga, Zotcheva, Svedahl, Nilsen, Skarpsno (CR62) 2019; 16 Fine, Gray (CR33) 1999; 94 Thompson, Karpe, Lafontan, Frayn (CR63) 2012; 92 Ueshima, Sekikawa, Miura, Turin, Takashima, Kita (CR19) 2008; 118 Dipietro (CR9) 2001; 56 Østergaard, Grønbæk, Schnohr, Sørensen, Heitmann (CR15) 2010; 34 CR18 Saint-Maurice, Coughlan, Kelly, Keadle, Cook, Carlson (CR44) 2019; 2 Moholdt, Lavie, Nauman (CR47) 2018; 71 CR13 CR56 CR10 Hu, Tuomilehto, Silventoinen, Barengo, Jousilahti (CR14) 2004; 25 Sanchez-lastra, Ding, Dalene, Ekelund, Tarp (CR30) 2021; 96 Wu, Tsai, Tsao, Chiu, Tsai, Lu (CR23) 2017; 46 Mok, Khaw, Luben, Wareham, Brage (CR46) 2019; 365 Lavie, Carbone, Kachur, O’keefe, Elagizi (CR71) 2019; 18 Lu, Hajifathalian, Ezzati, Woodward, Rimm, Danaei (CR48) 2014; 383 Wannamethee, Shaper, Walker (CR45) 1998; 351 Dyrstad, Hansen, Holme, Anderssen (CR68) 2014; 46 Lewington, Thomsen, Davidsen, Sherliker, Clarke (CR12) 2003; 10 Myrskyla, Chang (CR54) 2009; 20 Koster, Harris, Moore, Schatzkin, Hollenbeck, Van Eijk (CR4) 2009; 169 Pang, Holmes, Kartsonaki, Guo, Yang, Bian (CR51) 2017; 71 Lavie, Ozemek, Carbone, Katzmarzyk, Blair (CR64) 2019; 124 Hu, Willett, Li, Stampfer, Colditz, Manson (CR5) 2004; 351 Bellocco, Jia, Ye, Lagerros (CR6) 2010; 25 Wang, Tang, Guo, Tao, Liu, Li, Bin (CR55) 2017; 30 Bull, Al-, Biddle, Borodulin, Buman, Cardon (CR2) 2020; 54 CR29 Riebe, Blissmer, Greaney, Ewing Garber, Lees, Clark (CR8) 2009; 21 CR28 CR27 Heymsfield, Wadden (CR1) 2017; 376 Arnett, Blumenthal, Albert, Buroker, Goldberger, Hahn (CR22) 2019; 74 CR24 CR66 Lavie, Laddu, Arena, Ortega, Alpert, Kushner (CR70) 2018; 72 Orsini, Bellocco, Bottai, Pagano, Michaelsson, Wolk (CR60) 2008; 264 Lee, Pedley, Hoffmann, Massaro, Fox (CR57) 2016; 68 Eckel, Jakicic, Ard, De Jesus, Houston Miller, Hubbard (CR42) 2014; 63 Fletcher, Landolfo, Niebauer, Ozemek, Arena, Lavie (CR69) 2018; 72 Chen, Copeland, Vedanthan, Grant, Lee, Gu (CR50) 2013; 347 Huang, Jiang, Xu, Zhang, Sen, Zhu, Jin (CR53) 2020; 10 CJ Lavie (1195_CR70) 2018; 72 B Williams (1195_CR25) 2018; 39 N Orsini (1195_CR60) 2008; 264 S Lewington (1195_CR12) 2003; 10 H Ueshima (1195_CR19) 2008; 118 D Thompson (1195_CR63) 2012; 92 SB Heymsfield (1195_CR1) 2017; 376 FLJ Visseren (1195_CR21) 2021; 42 PT Katzmarzyk (1195_CR7) 2006; 31 JN Østergaard (1195_CR15) 2010; 34 FB Hu (1195_CR5) 2004; 351 KGMM Alberti (1195_CR32) 2009; 120 M Myrskyla (1195_CR54) 2009; 20 CJ Lavie (1195_CR71) 2019; 18 AL Nordstoga (1195_CR62) 2019; 16 JJ Lee (1195_CR57) 2016; 68 1195_CR10 X Pi-Sunyer (1195_CR59) 2014; 3 G Hu (1195_CR61) 2005; 29 1195_CR56 G Hu (1195_CR14) 2004; 25 M Hamer (1195_CR36) 2019; 48 1195_CR13 R Bellocco (1195_CR6) 2010; 25 1195_CR18 GF Fletcher (1195_CR69) 2018; 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References_xml | – volume: 12 start-page: 680 year: 2011 end-page: 7 ident: CR67 article-title: Body mass index, waist circumference and waist-hip ratio: Which is the better discriminator of cardiovascular disease mortality risk? Evidence from an individual-participant meta-analysis of 82864 participants from nine cohort studies publication-title: Obes Rev contributor: fullname: Batty – volume: 68 start-page: 1509 year: 2016 end-page: 21 ident: CR57 article-title: Association of Changes in Abdominal Fat Quantity and Quality With Incident Cardiovascular Disease Risk Factors publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2016.06.067 contributor: fullname: Fox – volume: 383 start-page: 970 year: 2014 end-page: 83 ident: CR48 article-title: Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: A pooled analysis of 97 prospective cohorts with 1·8 million participants publication-title: Lancet. doi: 10.1016/S0140-6736(13)61836-X contributor: fullname: Danaei – volume: 11 start-page: 741 year: 2010 end-page: 52 ident: CR49 article-title: Body-mass index and cancer mortality in the Asia-Pacific Cohort Studies Collaboration: Pooled analyses of 424 519 participants publication-title: Lancet Oncol doi: 10.1016/S1470-2045(10)70141-8 contributor: fullname: Ho – volume: 359 start-page: j4849 year: 2017 ident: CR58 article-title: Effects of weight loss interventions for adults who are obese on mortality, cardiovascular disease, and cancer: systematic review and meta-analysis publication-title: BMJ. doi: 10.1136/bmj.j4849 contributor: fullname: Robertson – volume: 43 start-page: 1575 year: 2011 end-page: 81 ident: CR26 article-title: 2011 compendium of physical activities: A second update of codes and MET values publication-title: Med Sci Sports Exerc. doi: 10.1249/MSS.0b013e31821ece12 contributor: fullname: Tudor-Locke – volume: 29 start-page: 894 year: 2005 end-page: 902 ident: CR61 article-title: The effects of physical activity and body mass index on cardiovascular, cancer and all-cause mortality among 47 212 middle-aged Finnish men and women publication-title: Int J Obes doi: 10.1038/sj.ijo.0802870 contributor: fullname: Jousilahti – ident: CR39 – volume: 72 start-page: 1622 year: 2018 end-page: 39 ident: CR69 article-title: Promoting Physical Activity and Exercise: JACC Health Promotion Series publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2018.08.2141 contributor: fullname: Lavie – volume: 10 start-page: 1 year: 2020 end-page: 12 ident: CR53 article-title: Adiposity change and mortality in middle-aged to older Chinese: An 8-year follow-up of the Guangzhou Biobank Cohort Study publication-title: BMJ Open doi: 10.1136/bmjopen-2020-039239 contributor: fullname: Jin – volume: 56 start-page: 13 year: 2001 end-page: 22 ident: CR9 article-title: Physical Activity in Aging: Changes in Patterns and Their Relationship to Health and Function publication-title: J s Gerontol Ser A. doi: 10.1093/gerona/56.suppl_2.13 contributor: fullname: Dipietro – volume: 92 start-page: 157 year: 2012 end-page: 91 ident: CR63 article-title: Physical activity and exercise in the regulation of human adipose tissue physiology publication-title: Physiol Rev doi: 10.1152/physrev.00012.2011 contributor: fullname: Frayn – ident: CR29 – volume: 145 start-page: 1245 year: 2019 end-page: 53 ident: CR52 article-title: Central adiposity in relation to risk of liver cancer in Chinese adults: A prospective study of 0.5 million people publication-title: Int J Cancer doi: 10.1002/ijc.32148 contributor: fullname: Bian – volume: 93 start-page: 359 year: 2013 end-page: 404 ident: CR65 article-title: Pathophysiology of human visceral obesity: An update publication-title: Physiol Rev doi: 10.1152/physrev.00033.2011 contributor: fullname: Després – volume: 320 start-page: 2020 year: 2018 end-page: 8 ident: CR17 article-title: The physical activity guidelines for Americans publication-title: Jama. doi: 10.1001/jama.2018.14854 contributor: fullname: Galuska – volume: 39 start-page: 3021 year: 2018 end-page: 104 ident: CR25 article-title: 2018 ESC/ESH Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Cardiology (ESC) and the European Society of Hypertension (ESH) publication-title: Eur Heart J. doi: 10.1093/eurheartj/ehy339 contributor: fullname: Burnier – volume: 25 start-page: 16 year: 2016 end-page: 27 ident: CR41 article-title: Global cancer incidence and mortality rates and trends - An update publication-title: Cancer Epidemiol Biomarkers Prev doi: 10.1158/1055-9965.EPI-15-0578 contributor: fullname: Jemal – volume: 63 start-page: 2960 year: 2014 end-page: 84 ident: CR42 article-title: 2013 AHA/ACC guideline on lifestyle management to reduce cardiovascular risk: A report of the American college of cardiology/American heart association task force on practice guidelines publication-title: J Am Coll Cardiol. doi: 10.1016/j.jacc.2013.11.003 contributor: fullname: Hubbard – volume: 74 start-page: e177 year: 2019 end-page: 232 ident: CR22 article-title: 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines publication-title: J Am Coll Cardiol. doi: 10.1016/j.jacc.2019.03.010 contributor: fullname: Hahn – volume: 20 start-page: 840 year: 2009 end-page: 8 ident: CR54 article-title: Weight change, initial bmi, and mortality among middle- and older-aged adults publication-title: Epidemiology. doi: 10.1097/EDE.0b013e3181b5f520 contributor: fullname: Chang – volume: 347 start-page: 1 year: 2013 end-page: 19 ident: CR50 article-title: Association between body mass index and cardiovascular disease mortality in east Asians and south Asians: Pooled analysis of prospective data from the Asia Cohort Consortium publication-title: BMJ. doi: 10.1136/bmj.f5446 contributor: fullname: Gu – volume: 120 start-page: 1640 year: 2009 end-page: 5 ident: CR32 article-title: Harmonizing the metabolic syndrome: A joint interim statement of the international diabetes federation task force on epidemiology and prevention; National heart, lung, and blood institute; American heart association; World heart federation; International publication-title: Circulation. doi: 10.1161/CIRCULATIONAHA.109.192644 contributor: fullname: Donato – volume: 130 start-page: 949 year: 2017 end-page: 57 ident: CR16 article-title: Interaction of Physical Activity and Body Mass Index on Mortality in Coronary Heart Disease: Data from the Nord-Trøndelag Health Study publication-title: Am J Med doi: 10.1016/j.amjmed.2017.01.043 contributor: fullname: Nauman – volume: 46 start-page: 328 year: 2015 end-page: 38 ident: CR40 article-title: Global Overview of the Epidemiology of Atherosclerotic Cardiovascular Disease publication-title: Arch Med Res doi: 10.1016/j.arcmed.2015.06.006 contributor: fullname: Lozano – volume: 2 start-page: e190355 year: 2019 ident: CR44 article-title: Association of Leisure-Time Physical Activity Across the Adult Life Course With All-Cause and Cause-Specific Mortality publication-title: JAMA Netw open doi: 10.1001/jamanetworkopen.2019.0355 contributor: fullname: Carlson – volume: 118 start-page: 2702 year: 2008 end-page: 9 ident: CR19 article-title: Cardiovascular disease and risk factors in Asia: A selected review publication-title: Circulation. doi: 10.1161/CIRCULATIONAHA.108.790048 contributor: fullname: Kita – volume: 18 start-page: 292 year: 2019 end-page: 8 ident: CR71 article-title: Effects of Physical Activity, Exercise, and Fitness on Obesity-Related Morbidity and Mortality publication-title: Curr Sports Med Rep doi: 10.1249/JSR.0000000000000623 contributor: fullname: Elagizi – volume: 31 start-page: 271 year: 2006 end-page: 6 ident: CR7 article-title: Independent effects of waist circumference and physical activity on all-cause mortality in Canadian women publication-title: Appl Physiol Nutr Metab doi: 10.1139/h05-038 contributor: fullname: Craig – volume: 3 start-page: 387 year: 2014 end-page: 91 ident: CR59 article-title: The look AHEAD trial: a review and discussion of its outcomes publication-title: Curr Nutr Rep doi: 10.1007/s13668-014-0099-x contributor: fullname: Pi-Sunyer – volume: 376 start-page: 254 year: 2017 end-page: 66 ident: CR1 article-title: Mechanisms, pathophysiology, and management of obesity publication-title: N Engl J Med doi: 10.1056/NEJMra1514009 contributor: fullname: Wadden – volume: 96 start-page: 105 year: 2021 end-page: 19 ident: CR30 article-title: Physical Activity and Mortality Across Levels of Adiposity publication-title: Mayo Clin Proc doi: 10.1016/j.mayocp.2020.06.049 contributor: fullname: Tarp – volume: 68 start-page: 394 year: 2018 end-page: 424 ident: CR20 article-title: Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries publication-title: CA Cancer J Clin doi: 10.3322/caac.21492 contributor: fullname: Jemal – volume: 351 start-page: 1603 year: 1998 end-page: 8 ident: CR45 article-title: Changes in physical activity, mortality, and incidence of coronary heart disease in older men publication-title: Lancet. doi: 10.1016/S0140-6736(97)12355-8 contributor: fullname: Walker – volume: 25 start-page: 2212 year: 2004 end-page: 9 ident: CR14 article-title: Joint effects of physical activity, body mass index, waist circumference and waist-to-hip ratio with the risk of cardiovascular disease among middle-aged Finnish men and women publication-title: Eur Heart J doi: 10.1016/j.ehj.2004.10.020 contributor: fullname: Jousilahti – volume: 34 start-page: 760 year: 2010 end-page: 9 ident: CR15 article-title: Combined effects of weight loss and physical activity on all-cause mortality of overweight men and women publication-title: Int J Obes doi: 10.1038/ijo.2009.274 contributor: fullname: Heitmann – ident: CR18 – volume: 321 start-page: 602 year: 2019 end-page: 3 ident: CR34 article-title: Using the E-value to assess the potential effect of unmeasured confounding in observational studies publication-title: Jama. doi: 10.1001/jama.2018.21554 contributor: fullname: Arterburn – ident: CR66 – volume: 9 start-page: 1 year: 2012 end-page: 14 ident: CR3 article-title: Leisure Time Physical Activity of Moderate to Vigorous Intensity and Mortality: A Large Pooled Cohort Analysis publication-title: PLoS Med doi: 10.1371/journal.pmed.1001335 contributor: fullname: Katki – ident: CR37 – ident: CR10 – volume: 54 start-page: 1451 year: 2020 end-page: 62 ident: CR2 article-title: World Health Organization 2020 guidelines on physical activity and sedentary behaviour publication-title: Br J Sports Med doi: 10.1136/bjsports-2020-102955 contributor: fullname: Cardon – volume: 42 start-page: 3227 year: 2021 end-page: 337 ident: CR21 article-title: 2021 ESC Guidelines on cardiovascular disease prevention in clinical practice publication-title: Eur Heart J. doi: 10.1093/eurheartj/ehab484 contributor: fullname: Bäck – volume: 71 start-page: 1094 year: 2018 end-page: 101 ident: CR47 article-title: Sustained Physical Activity, Not Weight Loss, Associated With Improved Survival in Coronary Heart Disease publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2018.01.011 contributor: fullname: Nauman – volume: 71 start-page: 1059 year: 2017 end-page: 67 ident: CR51 article-title: Young adulthood and adulthood adiposity in relation to incidence of pancreatic cancer: A prospective study of 0.5 million Chinese adults and a meta-analysis publication-title: J Epidemiol Community Health contributor: fullname: Bian – volume: 16 start-page: 1 year: 2019 end-page: 8 ident: CR62 article-title: Long-term changes in body weight and physical activity in relation to all-cause and cardiovascular mortality: The HUNT study publication-title: Int J Behav Nutr Phys Act doi: 10.1186/s12966-019-0809-2 contributor: fullname: Skarpsno – ident: CR56 – ident: CR27 – volume: 150 start-page: 341 year: 1999 end-page: 53 ident: CR11 article-title: Underestimation of risk associations due to regression dilution in long-term follow-up of prospective studies publication-title: Am J Epidemiol doi: 10.1093/oxfordjournals.aje.a010013 contributor: fullname: Marmot – volume: 264 start-page: 442 year: 2008 end-page: 51 ident: CR60 article-title: Combined effects of obesity and physical activity in predicting mortality among men publication-title: J Intern Med doi: 10.1111/j.1365-2796.2008.01985.x contributor: fullname: Wolk – volume: 124 start-page: 799 year: 2019 end-page: 815 ident: CR64 article-title: Sedentary Behavior, Exercise, and Cardiovascular Health publication-title: Circ Res doi: 10.1161/CIRCRESAHA.118.312669 contributor: fullname: Blair – volume: 10 start-page: 143 year: 2003 end-page: 8 ident: CR12 article-title: Regression dilution bias in blood total and high-density lipoprotein cholesterol and blood pressure in the glostrup and framingham prospective studies publication-title: Eur J Prev Cardiol doi: 10.1177/174182670301000210 contributor: fullname: Clarke – volume: 29 start-page: e45 year: 2018 ident: CR35 article-title: and R package for computing E-values publication-title: Epidemiology. doi: 10.1097/EDE.0000000000000864 contributor: fullname: VanderWeele – volume: 46 start-page: 99 year: 2014 end-page: 106 ident: CR68 article-title: Comparison of self-reported versus accelerometer-measured physical activity publication-title: Med Sci Sports Exerc doi: 10.1249/MSS.0b013e3182a0595f contributor: fullname: Anderssen – volume: 94 start-page: 496 year: 1999 end-page: 509 ident: CR33 article-title: A Proportional Hazards Model for the Subdistribution of a Competing Risk publication-title: J Am Stat Assoc doi: 10.1080/01621459.1999.10474144 contributor: fullname: Gray – volume: 48 start-page: 1161 year: 2019 end-page: 6 ident: CR36 article-title: Examining associations between physical activity and cardiovascular mortality using negative control outcomes publication-title: Int J Epidemiol doi: 10.1093/ije/dyy272 contributor: fullname: Stamatakis – ident: CR38 – volume: 116 start-page: 2110 year: 2007 ident: CR43 article-title: Physical activity and reduced risk of cardiovascular events: potential mediating mechanisms publication-title: Circulation. doi: 10.1161/CIRCULATIONAHA.107.729939 contributor: fullname: Lee – ident: CR31 – volume: 72 start-page: 1506 year: 2018 end-page: 31 ident: CR70 article-title: Healthy Weight and Obesity Prevention: JACC Health Promotion Series publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2018.08.1037 contributor: fullname: Kushner – ident: CR13 – volume: 30 start-page: 79 year: 2017 end-page: 87 ident: CR55 article-title: BMI and BMI Changes to All-cause Mortality among the Elderly in Beijing: a 20-year Cohort Study publication-title: Biomed Environ Sci contributor: fullname: Bin – volume: 169 start-page: 1344 year: 2009 end-page: 51 ident: CR4 article-title: Joint associations of adiposity and physical activity with mortality publication-title: Am J Epidemiol doi: 10.1093/aje/kwp053 contributor: fullname: Van Eijk – volume: 351 start-page: 2694 year: 2004 end-page: 703 ident: CR5 article-title: Adiposity as compared with physical activity in predicting mortality among women publication-title: N Engl J Med doi: 10.1056/NEJMoa042135 contributor: fullname: Manson – volume: 21 start-page: 1159 year: 2009 end-page: 78 ident: CR8 article-title: The relationship between obesity, physical activity, and physical function in older adults publication-title: J Aging Health doi: 10.1177/0898264309350076 contributor: fullname: Clark – ident: CR28 – volume: 365 start-page: l2323 year: 2019 ident: CR46 article-title: Physical activity trajectories and mortality: population based cohort study publication-title: BMJ. doi: 10.1136/bmj.l2323 contributor: fullname: Brage – volume: 25 start-page: 777 year: 2010 end-page: 88 ident: CR6 article-title: Effects of physical activity, body mass index, waist-to-hip ratio and waist circumference on total mortality risk in the Swedish National March Cohort publication-title: Eur J Epidemiol doi: 10.1007/s10654-010-9497-6 contributor: fullname: Lagerros – ident: CR24 – volume: 46 start-page: 1744 year: 2017 end-page: 1744g ident: CR23 article-title: Cohort Profile: The Taiwan MJ Cohort: Half a million Chinese with repeated health surveillance data publication-title: Int J Epidemiol doi: 10.1093/ije/dyw282 contributor: fullname: Lu – volume: 376 start-page: 254 year: 2017 ident: 1195_CR1 publication-title: N Engl J Med doi: 10.1056/NEJMra1514009 contributor: fullname: SB Heymsfield – volume: 68 start-page: 1509 year: 2016 ident: 1195_CR57 publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2016.06.067 contributor: fullname: JJ Lee – volume: 11 start-page: 741 year: 2010 ident: 1195_CR49 publication-title: Lancet Oncol doi: 10.1016/S1470-2045(10)70141-8 contributor: fullname: CL Parr – ident: 1195_CR66 – volume: 383 start-page: 970 year: 2014 ident: 1195_CR48 publication-title: Lancet. doi: 10.1016/S0140-6736(13)61836-X contributor: fullname: Y Lu – volume: 72 start-page: 1506 year: 2018 ident: 1195_CR70 publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2018.08.1037 contributor: fullname: CJ Lavie – ident: 1195_CR37 – ident: 1195_CR24 – volume: 74 start-page: e177 year: 2019 ident: 1195_CR22 publication-title: J Am Coll Cardiol. doi: 10.1016/j.jacc.2019.03.010 contributor: fullname: DK Arnett – volume: 30 start-page: 79 year: 2017 ident: 1195_CR55 publication-title: Biomed Environ Sci contributor: fullname: YF Wang – volume: 365 start-page: l2323 year: 2019 ident: 1195_CR46 publication-title: BMJ. doi: 10.1136/bmj.l2323 contributor: fullname: A Mok – volume: 29 start-page: 894 year: 2005 ident: 1195_CR61 publication-title: Int J Obes doi: 10.1038/sj.ijo.0802870 contributor: fullname: G Hu – volume: 56 start-page: 13 year: 2001 ident: 1195_CR9 publication-title: J s Gerontol Ser A. doi: 10.1093/gerona/56.suppl_2.13 contributor: fullname: L Dipietro – ident: 1195_CR39 doi: 10.1016/S2214-109X(18)30357-7 – volume: 347 start-page: 1 year: 2013 ident: 1195_CR50 publication-title: BMJ. doi: 10.1136/bmj.f5446 contributor: fullname: Y Chen – volume: 31 start-page: 271 year: 2006 ident: 1195_CR7 publication-title: Appl Physiol Nutr Metab doi: 10.1139/h05-038 contributor: fullname: PT Katzmarzyk – ident: 1195_CR27 – volume: 321 start-page: 602 year: 2019 ident: 1195_CR34 publication-title: Jama. doi: 10.1001/jama.2018.21554 contributor: fullname: S Haneuse – volume: 12 start-page: 680 year: 2011 ident: 1195_CR67 publication-title: Obes Rev doi: 10.1111/j.1467-789X.2011.00879.x contributor: fullname: S Czernichow – ident: 1195_CR13 doi: 10.1016/j.mayocp.2021.11.026 – volume: 2 start-page: e190355 year: 2019 ident: 1195_CR44 publication-title: JAMA Netw open doi: 10.1001/jamanetworkopen.2019.0355 contributor: fullname: PF Saint-Maurice – volume: 9 start-page: 1 year: 2012 ident: 1195_CR3 publication-title: PLoS Med doi: 10.1371/journal.pmed.1001335 contributor: fullname: SC Moore – volume: 130 start-page: 949 year: 2017 ident: 1195_CR16 publication-title: Am J Med doi: 10.1016/j.amjmed.2017.01.043 contributor: fullname: T Moholdt – volume: 124 start-page: 799 year: 2019 ident: 1195_CR64 publication-title: Circ Res doi: 10.1161/CIRCRESAHA.118.312669 contributor: fullname: CJ Lavie – volume: 39 start-page: 3021 year: 2018 ident: 1195_CR25 publication-title: Eur Heart J. doi: 10.1093/eurheartj/ehy339 contributor: fullname: B Williams – ident: 1195_CR38 – volume: 42 start-page: 3227 year: 2021 ident: 1195_CR21 publication-title: Eur Heart J. doi: 10.1093/eurheartj/ehab484 contributor: fullname: FLJ Visseren – volume: 48 start-page: 1161 year: 2019 ident: 1195_CR36 publication-title: Int J Epidemiol doi: 10.1093/ije/dyy272 contributor: fullname: M Hamer – volume: 16 start-page: 1 year: 2019 ident: 1195_CR62 publication-title: Int J Behav Nutr Phys Act doi: 10.1186/s12966-019-0809-2 contributor: fullname: AL Nordstoga – volume: 72 start-page: 1622 year: 2018 ident: 1195_CR69 publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2018.08.2141 contributor: fullname: GF Fletcher – volume: 63 start-page: 2960 year: 2014 ident: 1195_CR42 publication-title: J Am Coll Cardiol. doi: 10.1016/j.jacc.2013.11.003 contributor: fullname: RH Eckel – volume: 71 start-page: 1094 year: 2018 ident: 1195_CR47 publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2018.01.011 contributor: fullname: T Moholdt – volume: 46 start-page: 99 year: 2014 ident: 1195_CR68 publication-title: Med Sci Sports Exerc doi: 10.1249/MSS.0b013e3182a0595f contributor: fullname: SM Dyrstad – volume: 10 start-page: 1 year: 2020 ident: 1195_CR53 publication-title: BMJ Open doi: 10.1136/bmjopen-2020-039239 contributor: fullname: YY Huang – volume: 351 start-page: 2694 year: 2004 ident: 1195_CR5 publication-title: N Engl J Med doi: 10.1056/NEJMoa042135 contributor: fullname: FB Hu – volume: 29 start-page: e45 year: 2018 ident: 1195_CR35 publication-title: Epidemiology. doi: 10.1097/EDE.0000000000000864 contributor: fullname: MB Mathur – volume: 25 start-page: 2212 year: 2004 ident: 1195_CR14 publication-title: Eur Heart J doi: 10.1016/j.ehj.2004.10.020 contributor: fullname: G Hu – ident: 1195_CR31 – volume: 71 start-page: 1059 year: 2017 ident: 1195_CR51 publication-title: J Epidemiol Community Health doi: 10.1136/jech-2017-208895 contributor: fullname: Y Pang – volume: 34 start-page: 760 year: 2010 ident: 1195_CR15 publication-title: Int J Obes doi: 10.1038/ijo.2009.274 contributor: fullname: JN Østergaard – ident: 1195_CR28 – volume: 359 start-page: j4849 year: 2017 ident: 1195_CR58 publication-title: BMJ. doi: 10.1136/bmj.j4849 contributor: fullname: C Ma – volume: 43 start-page: 1575 year: 2011 ident: 1195_CR26 publication-title: Med Sci Sports Exerc. doi: 10.1249/MSS.0b013e31821ece12 contributor: fullname: BE Ainsworth – volume: 94 start-page: 496 year: 1999 ident: 1195_CR33 publication-title: J Am Stat Assoc doi: 10.1080/01621459.1999.10474144 contributor: fullname: JP Fine – volume: 92 start-page: 157 year: 2012 ident: 1195_CR63 publication-title: Physiol Rev doi: 10.1152/physrev.00012.2011 contributor: fullname: D Thompson – volume: 116 start-page: 2110 year: 2007 ident: 1195_CR43 publication-title: Circulation. doi: 10.1161/CIRCULATIONAHA.107.729939 contributor: fullname: S Mora – volume: 10 start-page: 143 year: 2003 ident: 1195_CR12 publication-title: Eur J Prev Cardiol doi: 10.1177/174182670301000210 contributor: fullname: S Lewington – volume: 25 start-page: 16 year: 2016 ident: 1195_CR41 publication-title: Cancer Epidemiol Biomarkers Prev doi: 10.1158/1055-9965.EPI-15-0578 contributor: fullname: LA Torre – volume: 320 start-page: 2020 year: 2018 ident: 1195_CR17 publication-title: Jama. doi: 10.1001/jama.2018.14854 contributor: fullname: KL Piercy – volume: 169 start-page: 1344 year: 2009 ident: 1195_CR4 publication-title: Am J Epidemiol doi: 10.1093/aje/kwp053 contributor: fullname: A Koster – volume: 150 start-page: 341 year: 1999 ident: 1195_CR11 publication-title: Am J Epidemiol doi: 10.1093/oxfordjournals.aje.a010013 contributor: fullname: R Clarke – volume: 351 start-page: 1603 year: 1998 ident: 1195_CR45 publication-title: Lancet. doi: 10.1016/S0140-6736(97)12355-8 contributor: fullname: SG Wannamethee – volume: 96 start-page: 105 year: 2021 ident: 1195_CR30 publication-title: Mayo Clin Proc doi: 10.1016/j.mayocp.2020.06.049 contributor: fullname: MA Sanchez-lastra – volume: 18 start-page: 292 year: 2019 ident: 1195_CR71 publication-title: Curr Sports Med Rep doi: 10.1249/JSR.0000000000000623 contributor: fullname: CJ Lavie – ident: 1195_CR56 doi: 10.1136/bmj.l5584 – volume: 264 start-page: 442 year: 2008 ident: 1195_CR60 publication-title: J Intern Med doi: 10.1111/j.1365-2796.2008.01985.x contributor: fullname: N Orsini – ident: 1195_CR29 – ident: 1195_CR18 doi: 10.1016/bs.afnr.2015.07.001 – volume: 145 start-page: 1245 year: 2019 ident: 1195_CR52 publication-title: Int J Cancer doi: 10.1002/ijc.32148 contributor: fullname: Y Pang – volume: 25 start-page: 777 year: 2010 ident: 1195_CR6 publication-title: Eur J Epidemiol doi: 10.1007/s10654-010-9497-6 contributor: fullname: R Bellocco – volume: 93 start-page: 359 year: 2013 ident: 1195_CR65 publication-title: Physiol Rev doi: 10.1152/physrev.00033.2011 contributor: fullname: A Tchernof – volume: 3 start-page: 387 year: 2014 ident: 1195_CR59 publication-title: Curr Nutr Rep doi: 10.1007/s13668-014-0099-x contributor: fullname: X Pi-Sunyer – volume: 21 start-page: 1159 year: 2009 ident: 1195_CR8 publication-title: J Aging Health doi: 10.1177/0898264309350076 contributor: fullname: D Riebe – ident: 1195_CR10 doi: 10.1007/s40273-014-0243-x – volume: 20 start-page: 840 year: 2009 ident: 1195_CR54 publication-title: Epidemiology. doi: 10.1097/EDE.0b013e3181b5f520 contributor: fullname: M Myrskyla – volume: 54 start-page: 1451 year: 2020 ident: 1195_CR2 publication-title: Br J Sports Med doi: 10.1136/bjsports-2020-102955 contributor: fullname: FC Bull – volume: 120 start-page: 1640 year: 2009 ident: 1195_CR32 publication-title: Circulation. doi: 10.1161/CIRCULATIONAHA.109.192644 contributor: fullname: KGMM Alberti – volume: 46 start-page: 1744 year: 2017 ident: 1195_CR23 publication-title: Int J Epidemiol doi: 10.1093/ije/dyw282 contributor: fullname: X Wu – volume: 46 start-page: 328 year: 2015 ident: 1195_CR40 publication-title: Arch Med Res doi: 10.1016/j.arcmed.2015.06.006 contributor: fullname: S Barquera – volume: 118 start-page: 2702 year: 2008 ident: 1195_CR19 publication-title: Circulation. doi: 10.1161/CIRCULATIONAHA.108.790048 contributor: fullname: H Ueshima – volume: 68 start-page: 394 year: 2018 ident: 1195_CR20 publication-title: CA Cancer J Clin doi: 10.3322/caac.21492 contributor: fullname: F Bray |
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The relationship between joint changes in physical activity and adiposity with mortality is not well understood. We examined the association of... Abstract Background The relationship between joint changes in physical activity and adiposity with mortality is not well understood. We examined the... BackgroundThe relationship between joint changes in physical activity and adiposity with mortality is not well understood. We examined the association of... BACKGROUNDThe relationship between joint changes in physical activity and adiposity with mortality is not well understood. We examined the association of... |
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SubjectTerms | 692/499 692/699 Adipose tissue Attenuation Body fat Body mass index Body size Body weight Cancer Cardiovascular disease Cardiovascular diseases Epidemiology Exercise Guidelines Health Promotion and Disease Prevention Heart diseases Internal Medicine Medicine Medicine & Public Health Metabolic Diseases Mortality Mortality risk Overweight Physical activity Public Health Risk analysis Risk factors |
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Title | Changes in physical activity and adiposity with all-cause, cardiovascular disease, and cancer mortality |
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