Surfactant Protein C Mutations Are the Basis of a Significant Portion of Adult Familial Pulmonary Fibrosis in a Dutch Cohort - van Moorsel, Coline H. M.; van Oosterhout, Matthijs F. M.; Barlo, Nicole P.; de Jong, Pim A.; van der Vis, Joanne J.; Ruven, Henk J. T.; van Es, H. Wouter; van den Bosch, Jules M. M.; Grutters, Jan C. (American journal of respiratory and critical care medicine, 2010)
Keywords: Adult; Aged; Aged, 80 and over; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Biological and medical sciences; Cohort Studies; Cysts; Families & family life; Family; Female; Genetic Predisposition to Disease - genetics; Hospitals; Humans; Idiopathic Interstitial Pneumonias - complications; Idiopathic Interstitial Pneumonias - genetics; Intensive care medicine; Lung diseases; Male; Medical prognosis; Medical records; Medical sciences; Middle Aged; Mutation; Mutation - genetics; Netherlands - epidemiology; Pedigree; Pneumology; Pneumonia; Polymerase Chain Reaction; Polymorphism, Genetic - genetics; Proteins; Pulmonary fibrosis; Pulmonary Fibrosis - etiology; Pulmonary Fibrosis - genetics; Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases; Pulmonary Surfactant-Associated Protein C - genetics; Statistics, Nonparametric; Surfactants; Netherlands; Lung disease; Intensive care; Respiratory disease; ABCA3; Idiopathic; Protein C; idiopathic pulmonary fibrosis; Surfactant; idiopathic interstitial pneumonia; lung cysts; Pulmonary fibrosis; Pulmonary surfactant; Cyst; Interstitial pneumonitis; Benign neoplasm; Mutation; Resuscitation