Arousal and drug abuse

• Published in: Behavioural brain research Vol. 333; pp. 276 - 281
• Main Authors: Urbano, Francisco J., Bisagno, Verónica, Garcia-Rill, Edgar
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 30.08.2017
• Subjects: Animals; Arousal - physiology; Cocaine; Connexin 36; Dopamine; Humans; Modafinil; N- and P/Q-type calcium channels; Preconscious awareness; Substance-Related Disorders - physiopathology; Preconscious awareness; Cocaine; Dopamine; Modafinil; N- and P/Q-type calcium channels; Connexin 36

The reticular activating system (RAS) is not an amorphous region but distinct nuclei with specific membrane properties that dictate their firing during waking and sleep. The locus coeruleus and raphe nucleus fire during waking and slow wave sleep, with the pedunculopontine nucleus (PPN) firing durin...