Brain metabolite changes in cortical grey and normal‐appearing white matter in clinically early relapsing–remitting multiple sclerosis - Chard, D. T.; Griffin, C. M.; McLean, M. A.; Kapeller, P.; Kapoor, R.; Thompson, A. J.; Miller, D. H. (Brain (London, England : 1878), 2002)
Keywords: 1H‐MRSI = proton magnetic resonance spectroscopic imaging; 9HPT = nine hole peg test; Adult; Biological and medical sciences; BP = brain parenchymal; BPF = brain parenchymal fraction; Brain - metabolism; CGM = cortical grey matter; Cho = choline containing compounds; Cohort Studies; Cr = creatine and phosphocreatine; EDSS = expanded disability status scale; Female; FSE = fast spin echo; Glx = glutamate plus glutamine; GM = grey matter; GMF = grey matter fraction; grey matter; Humans; Ins = myo‐inositol; Linear Models; Magnetic Resonance Spectroscopy - statistics & numerical data; Male; Medical sciences; metabolite concentrations; Middle Aged; MSFC = multiple sclerosis functional composite; multiple sclerosis; Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis; Multiple Sclerosis, Relapsing-Remitting - metabolism; NAWM = normal‐appearing white matter; NC = normal control; Neurology; normal‐appearing white matter; PASAT = paced auditory serial addition test; PRESS = point resolved spectroscopic; proton magnetic resonance spectroscopic imaging; Statistics, Nonparametric; TI = total intracranial; tNAA = N‐acetyl‐aspartate plus N‐acetyl‐aspartyl‐glutamate; TWT = timed walk test; WM = white matter; WMF = white matter fraction; Human; Nervous system diseases; Relapse; Multiple sclerosis; Pathophysiology; Grey matter; NMR spectrometry; Metabolism; Nuclear magnetic resonance imaging; Inflammatory disease; Central nervous system disease; Medical imagery; Remission; Brain (vertebrata)