Photoinactivation of Escherichia coli (SURE2) without intracellular uptake of the photosensitizer

• Published in: Journal of applied microbiology Vol. 114; no. 1; pp. 36 - 43
• Main Authors: Preuß, A., Zeugner, L., Hackbarth, S., Faustino, M.A.F., Neves, M.G.P.M.S., Cavaleiro, J.A.S., Roeder, B.
• Format: Journal Article
• Language: English
• Published: Oxford Blackwell 01.01.2013; Oxford University Press
• Subjects: antibiotics resistance; Bacteria; Biological and medical sciences; E coli; Escherichia coli; Escherichia coli - drug effects; Fundamental and applied biological sciences. Psychology; Gram-negative bacteria; intracellular uptake; Microbial Viability; Microbiology; Microscopy, Confocal; photodynamic inactivation; Photosensitizing Agents - metabolism; Photosensitizing Agents - pharmacology; phototoxicity; Porphyrins - metabolism; Porphyrins - pharmacology; reactive oxygen species; singlet oxygen; Oxygen; antibiotics resistance; Applied microbiology; Escherichia coli; photodynamic inactivation; intracellular uptake; Inactivation; Uptake; Resistance; Antibiotic; singlet oxygen; reactive oxygen species; Phototoxicity; Bacteria; Intracellular; Photosensitizer; Enterobacteriaceae

Aim This study was performed to investigate the possibility to photodynamically inactivate Gram‐negative bacteria without intracellular uptake of the photosensitizer. The efficiency of the photodynamic growth inhibition of Escherichia coli (SURE2) was proved in a comparative study of a neutral and a...