Abstrakt interacts with and regulates the expression of sorting nexin-2

• Published in: Journal of cellular physiology Vol. 204; no. 1; pp. 210 - 218
• Main Authors: Abdul-Ghani, Mohammad, Hartman, Kristin L., Ngsee, Johnny K.
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.07.2005
• Subjects: Animals; Carrier Proteins - chemistry; Carrier Proteins - genetics; Carrier Proteins - metabolism; Cell Nucleus - metabolism; CHO Cells; Cricetinae; Culture Media, Serum-Free - pharmacology; Cytoplasm - metabolism; DEAD-box RNA Helicases; Gene Expression; Humans; Protein Structure, Tertiary; Protein Transport - physiology; RNA Helicases - chemistry; RNA Helicases - genetics; RNA Helicases - metabolism; RNA, Messenger - metabolism; Vesicular Transport Proteins - chemistry; Vesicular Transport Proteins - genetics; Vesicular Transport Proteins - metabolism

Protein sorting through vesicular compartments is highly regulated to maintain the integrity and signaling of intracellular organelles in eukaryotic cells. Sorting Nexin‐2 (SNX2) is involved in protein sorting in the trans‐Golgi network, endosome, and/or lysosome compartments, with loss of function...