Evidence of β-Cell Dedifferentiation in Human Type 2 Diabetes - Cinti, Francesca; Bouchi, Ryotaro; Kim-Muller, Ja Young; Ohmura, Yoshiaki; Sandoval, P. R.; Masini, Matilde; Marselli, Lorella; Suleiman, Mara; Ratner, Lloyd E.; Marchetti, Piero; Accili, Domenico (The journal of clinical endocrinology and metabolism, 2016)
Keywords: Aldehyde dehydrogenase; Aldehydes; Beta cells; Cell Dedifferentiation; Dehydrogenases; Diabetes; Diabetes mellitus (non-insulin dependent); Diabetes Mellitus, Type 2 - pathology; Forkhead Box Protein O1; Forkhead Transcription Factors - analysis; Glucagon; Glucagon - metabolism; Glucagon-Secreting Cells - physiology; Homeodomain Proteins - analysis; Humans; Immunohistochemistry; Insulin - metabolism; Insulin Secretion; Insulin-Secreting Cells - chemistry; Insulin-Secreting Cells - pathology; Insulin-Secreting Cells - physiology; Microscopy, Electron; Organ donors; Original; Pancreas; Progenitor cells; Somatostatin; Somatostatin - metabolism; Somatostatin-Secreting Cells - physiology; Transcription factors