Molecular Lipids Identify Cardiovascular Risk and Are Efficiently Lowered by Simvastatin and PCSK9 Deficiency - Tarasov, Kirill; Ekroos, Kim; Suoniemi, Matti; Kauhanen, Dimple; Sylvänne, Tuulia; Hurme, Reini; Gouni-Berthold, Ioanna; Berthold, Heiner K.; Kleber, Marcus E.; Laaksonen, Reijo; März, Winfried (The journal of clinical endocrinology and metabolism, 2014)
Keywords: Aged; Azetidines - therapeutic use; Cardiovascular disease; Cardiovascular diseases; Case-Control Studies; Ceramide; Cholesterol; Coronary artery disease; Coronary Artery Disease - blood; Coronary Artery Disease - drug therapy; Coronary Artery Disease - epidemiology; Drug development; Ezetimibe; Female; Follow-Up Studies; Genetic Association Studies; Genetic Predisposition to Disease; Heart diseases; Hot Topics in Translational Endocrinology; Humans; Hypolipidemic Agents - therapeutic use; Lipids; Lipids - blood; Macromolecular Substances - blood; Male; Middle Aged; Morbidity; Proprotein Convertase 9; Proprotein Convertases - deficiency; Proprotein Convertases - genetics; Randomized Controlled Trials as Topic; Risk Factors; Serine Endopeptidases - deficiency; Serine Endopeptidases - genetics; Simvastatin; Simvastatin - therapeutic use