Single‐cell immune profiling reveals long‐term changes in myeloid cells and identifies a novel subset of CD9+ monocytes associated with COVID‐19 hospitalization

• Published in: Journal of leukocyte biology Vol. 112; no. 5; pp. 1053 - 1063
• Main Authors: Pandori, William J., Padgett, Lindsey E., Alimadadi, Ahmad, Gutierrez, Norma A., Araujo, Daniel J., Huh, Christine J., Olingy, Claire E., Dinh, Huy Q., Wu, Runpei, Vijayanand, Pandurangan, Chee, Serena J., Ottensmeier, Christian H., Hedrick, Catherine C.
• Format: Journal Article
• Language: English
• Published: England John Wiley and Sons Inc 01.11.2022
• Subjects: COVID-19; Covid‐19 and Related Topics; Covid‐19 Special Section; CyTOF; Hospitalization; Humans; Interleukin-8 - metabolism; Lipopolysaccharides - metabolism; long‐COVID‐19; Monocytes; Myeloid Cells; nonclassical monocytes; Post-Acute COVID-19 Syndrome; SARS-CoV-2; Slan; T cells; Tetraspanin 29 - metabolism; Slan; SARS-CoV-2; nonclassical monocytes; T cells; CyTOF; long-COVID-19

Coronavirus disease 2019 (COVID‐19) caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection can result in severe immune dysfunction, hospitalization, and death. Many patients also develop long‐COVID‐19, experiencing symptoms months after infection. Although significant progr...