Effects of the NEDD8-Activating Enzyme Inhibitor MLN4924 on Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus - Chang, Pey-Jium; Chen, Lee-Wen; Chen, Li-Yu; Hung, Chien-Hui; Shih, Ying-Ju; Wang, Shie-Shan (Journal of virology, 2017)
Keywords: Antigens, Viral - metabolism; Butyric Acid - pharmacology; Cell Line, Tumor; Cell Proliferation; Cyclopentanes - pharmacology; Genome and Regulation of Viral Gene Expression; HEK293 Cells; Herpesvirus 8, Human - pathogenicity; Humans; Immediate-Early Proteins - genetics; Immunoglobulin J Recombination Signal Sequence-Binding Protein - genetics; Immunoglobulin J Recombination Signal Sequence-Binding Protein - metabolism; Nuclear Proteins - metabolism; Promoter Regions, Genetic - drug effects; Pyrimidines - pharmacology; Sarcoma, Kaposi - pathology; Sarcoma, Kaposi - virology; Tetradecanoylphorbol Acetate - pharmacology; Trans-Activators - genetics; Ubiquitin-Activating Enzymes - antagonists & inhibitors; Virus Activation - drug effects; ORF50; lytic reactivation; LANA; Kaposi's sarcoma-associated herpesvirus; KSHV; MLN4924