Comparative Effectiveness of Calcimimetic Agents for Secondary Hyperparathyroidism in Adults: A Systematic Review and Network Meta-analysis

• Published in: American journal of kidney diseases Vol. 76; no. 3; pp. 321 - 330
• Main Authors: Palmer, Suetonia C., Mavridis, Dimitris, Johnson, David W., Tonelli, Marcello, Ruospo, Marinella, Strippoli, Giovanni F.M.
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.09.2020
• Subjects: Calcimimetic; cardiovascular disease (CVD); cinacalcet; dialysis; end-stage renal disease (ESRD); etelcalcetide; evidence-based medicine (EBM); evocalcet; fracture; gastrointestinal side effects; hypocalcemia; mortality; nausea; network meta-analysis; parathyroid hormone (PTH); PTH target; randomized controlled trials (RCTs); renal failure; secondary hyperparathyroidism; systematic review; vomiting; dialysis; secondary hyperparathyroidism; randomized controlled trials (RCTs); evidence-based medicine (EBM); parathyroid hormone (PTH); gastrointestinal side effects; systematic review; PTH target; nausea; fracture; Calcimimetic; cinacalcet; hypocalcemia; evocalcet; etelcalcetide; end-stage renal disease (ESRD); renal failure; mortality; network meta-analysis; cardiovascular disease (CVD); vomiting

Comparative benefits and harms of calcimimetic agents used for the treatment of secondary hyperparathyroidism have not been well characterized. We sought to compare the effectiveness of 3 calcimimetic agents using published data. Systematic review of randomized controlled trials and network meta-ana...