Development of a Highly Effective African Swine Fever Virus Vaccine by Deletion of the I177L Gene Results in Sterile Immunity against the Current Epidemic Eurasia Strain

• Published in: Journal of virology Vol. 94; no. 7
• Main Authors: Borca, Manuel V., Ramirez-Medina, Elizabeth, Silva, Ediane, Vuono, Elizabeth, Rai, Ayushi, Pruitt, Sarah, Holinka, Lauren G., Velazquez-Salinas, Lauro, Zhu, James, Gladue, Douglas P.
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 17.03.2020
• Subjects: Vaccines and Antiviral Agents; African swine fever virus; vaccine; ASF; ASFV

Currently, there is no commercially available vaccine against African swine fever. Outbreaks of this disease are devastating the swine industry from Central Europe to East Asia, and they are being caused by circulating strains of African swine fever virus derived from the Georgia 2007 isolate. Here,...