Serial Section Array Scanning Electron Microscopy Analysis of Cells from Lung Autopsy Specimens following Fatal A/H1N1 2009 Pandemic Influenza Virus Infection

• Published in: Journal of virology Vol. 93; no. 19
• Main Authors: Kataoka, Michiyo, Ishida, Kinji, Ogasawara, Katsutoshi, Nozaki, Takayuki, Satoh, Yoh-Ichi, Sata, Tetsutaro, Sato, Yuko, Hasegawa, Hideki, Nakajima, Noriko
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01.10.2019
• Subjects: Virus-Cell Interactions; influenza virus; electron microscopy; autopsy

Generally, it is difficult to observe IAV particles in postmortem samples from patients with seasonal influenza. In fact, only a few viral antigens are detected in bronchial epithelial cells from autopsied lung sections. Previously, we detected many viral antigens in AEC-IIs from the lung. This was...