Glycan engineering of the SARS-CoV-2 receptor-binding domain elicits cross-neutralizing antibodies for SARS-related viruses - Shinnakasu, Ryo; Sakakibara, Shuhei; Yamamoto, Hiromi; Wang, Po-hung; Moriyama, Saya; Sax, Nicolas; Ono, Chikako; Yamanaka, Atsushi; Adachi, Yu; Onodera, Taishi; Sato, Takashi; Shinkai, Masaharu; et al. (The Journal of experimental medicine, 2021)
Keywords: Amino Acid Motifs; Animals; Antibodies, Viral - immunology; Broadly Neutralizing Antibodies - immunology; COVID-19 - genetics; COVID-19 - immunology; COVID-19 - prevention & control; COVID-19 Vaccines - genetics; COVID-19 Vaccines - immunology; Female; Humans; Infectious Disease and Host Defense; Male; Mice; Mice, Inbred BALB C; Polysaccharides - genetics; Polysaccharides - immunology; Protein Domains; SARS-CoV-2 - genetics; SARS-CoV-2 - immunology; Severe acute respiratory syndrome-related coronavirus - genetics; Severe acute respiratory syndrome-related coronavirus - immunology; Spike Glycoprotein, Coronavirus - genetics; Spike Glycoprotein, Coronavirus - immunology