Maternal immunization with pneumococcal polysaccharide vaccine in the Philippines

• Published in: Vaccine Vol. 21; no. 24; pp. 3451 - 3454
• Main Authors: Quiambao, B.P., Nohynek, H., Käyhty, H., Ollgren, J., Gozum, L., Gepanayao, C.P., Soriano, V., Mäkela, P.H.
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Oxford Elsevier Ltd 28.07.2003; Elsevier; Elsevier Limited
• Subjects: Adult; Age; Antibodies; Antibodies, Bacterial - analysis; Antibodies, Bacterial - biosynthesis; Babies; Bacterial diseases; Bacteriology; Biological and medical sciences; Confidence intervals; Data analysis; Disease; Female; Fetal Blood - immunology; Fundamental and applied biological sciences. Psychology; Health facilities; Human bacterial diseases; Humans; Immune response; Immunization; Immunization Programs; Immunogenicity; Infant, Newborn; Infants; Infectious diseases; Maternal immunization; Medical sciences; Meningitis; Microbiology; Mortality; Mothers; Philippines; Pneumococcal Vaccines - adverse effects; Pneumococcal Vaccines - immunology; Pneumococcus; Pregnancy; Pregnancy Trimester, Third - immunology; Serotyping; Staphylococcal infections, streptococcal infections, pneumococcal infections; Streptococcus infections; Streptococcus pneumoniae - immunology; Studies; Tropical medicine; Vaccines; Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies; Womens health; Philippines; Gambia; Papua New Guinea; Maternal immunization; Antibodies; Pneumococcus; Human; Immunization; Vaccine; Streptococcus pneumoniae; Infection; Pregnancy; Prevention; Streptococcaceae; Immunoprophylaxis; Streptococcal infection; Bacteriosis; Bacteria; Micrococcales; Female; Pneumococcal infection; Polysaccharide

A randomized, controlled study was conducted to evaluate the immunogenicity and reactogenicity of the 23-valent pneumococcal (Pnc) polysaccharide (PS) vaccine among pregnant women and to ascertain the transfer of anti-Pnc antibody (Ab) from mother to infant. One hundred and sixty women received eith...