Microbial profiling of dental plaque from mechanically ventilated patients

• Published in: Journal of medical microbiology Vol. 65; no. 2; pp. 147 - 159
• Main Authors: Sands, Kirsty M, Twigg, Joshua A, Lewis, Michael A O, Wise, Matt P, Marchesi, Julian R, Smith, Ann, Wilson, Melanie J, Williams, David W
• Format: Journal Article
• Language: English
• Published: England Microbiology Society 01.02.2016
• Subjects: Adult; Aged; Bacteria - classification; Bacteria - genetics; Bacteria - isolation & purification; Dental Plaque - complications; Dental Plaque - microbiology; Female; Humans; Male; Middle Aged; Molecular Sequence Data; Phylogeny; Pneumonia, Ventilator-Associated - etiology; Pneumonia, Ventilator-Associated - microbiology; Respiration, Artificial - adverse effects; Young Adult

Micro-organisms isolated from the oral cavity may translocate to the lower airways during mechanical ventilation (MV) leading to ventilator-associated pneumonia (VAP). Changes within the dental plaque microbiome during MV have been documented previously, primarily using culture-based techniques. The...