Glymphatic system clears extracellular tau and protects from tau aggregation and neurodegeneration - Ishida, Kazuhisa; Yamada, Kaoru; Nishiyama, Risa; Hashimoto, Tadafumi; Nishida, Itaru; Abe, Yoichiro; Yasui, Masato; Iwatsubo, Takeshi (The Journal of experimental medicine, 2022)
Keywords: Animals; Aquaporin 4 - deficiency; Aquaporin 4 - genetics; Aquaporin 4 - metabolism; Brain - metabolism; Brain - pathology; Brief Definitive Report; Extracellular Fluid - metabolism; Female; Glymphatic System - metabolism; Glymphatic System - pathology; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Mutant Proteins - cerebrospinal fluid; Mutant Proteins - genetics; Mutant Proteins - metabolism; Nerve Degeneration - metabolism; Nerve Degeneration - pathology; Protein Aggregation, Pathological - metabolism; tau Proteins - cerebrospinal fluid; tau Proteins - genetics; tau Proteins - metabolism