Thermal liquid biopsy for monitoring melanoma patients under surveillance during treatment: A pilot study

• Published in: Biochimica et biophysica acta. General subjects Vol. 1862; no. 8; pp. 1701 - 1710
• Main Authors: Velazquez-Campoy, Adrian, Vega, Sonia, Sanchez-Gracia, Oscar, Lanas, Angel, Rodrigo, Alberto, Kaliappan, Alagammai, Hall, Melissa Barousse, Nguyen, Taylor Q., Brock, Guy N., Chesney, Jason A., Garbett, Nichola C., Abian, Olga
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.08.2018
• Subjects: adjuvants; Adult; biopsy; Calorimetry, Differential Scanning; Case-Control Studies; clinical examination; decision making; differential scanning calorimetry; Differential scanning calorimetry (DSC); Differential Thermal Analysis; Early diagnostic and prognostic; Female; Humans; image analysis; immunotherapy; Liquid Biopsy; liquids; Male; Melanoma; Melanoma - blood; Melanoma - pathology; Melanoma - therapy; Middle Aged; monitoring; Monitoring, Physiologic - methods; Neoplasm Recurrence, Local - blood; Neoplasm Recurrence, Local - pathology; Neoplasm Recurrence, Local - therapy; Non-invasive test; Patient surveillance; patients; Pilot Projects; resection; MUSP; A; Differential scanning calorimetry (DSC); Melanoma; GAC; Patient surveillance; NED; Cp; Tc; AUC; CT; T; DSC; MC; w; IRB; Non-invasive test; Early diagnostic and prognostic; APn

Differential Scanning Calorimetry (DSC) is a technique traditionally used to study thermally induced macromolecular transitions, and it has recently been proposed as a novel approach for diagnosis and monitoring of several diseases. We report a pilot study applying Thermal Liquid Biopsy (TLB, DSC th...