Drosophila as a Model for Infectious Diseases

• Published in: International journal of molecular sciences Vol. 22; no. 5; p. 2724
• Main Authors: Harnish, J. Michael, Link, Nichole, Yamamoto, Shinya
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI 08.03.2021
• Subjects: Animals; Communicable Diseases - immunology; Communicable Diseases - metabolism; Communicable Diseases - microbiology; Communicable Diseases - virology; Drosophila melanogaster - immunology; Drosophila melanogaster - metabolism; Drosophila melanogaster - microbiology; Drosophila melanogaster - virology; Host-Pathogen Interactions; Immunity, Innate; Review; Signal Transduction; Virulence Factors - metabolism; pathogens and virulence factors; infection; immunity; Drosophila melanogaster; disease models

The fruit fly, Drosophila melanogaster, has been used to understand fundamental principles of genetics and biology for over a century. Drosophila is now also considered an essential tool to study mechanisms underlying numerous human genetic diseases. In this review, we will discuss how flies can be...