BCR-ABL1 compound mutants: prevalence, spectrum and correlation with tyrosine kinase inhibitor resistance in a consecutive series of Philadelphia chromosome-positive leukemia patients analyzed by NGS

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Bibliographic Details
Published inLeukemia Vol. 35; no. 7; pp. 2102 - 2107
Main Authors Soverini, Simona, Martelli, Margherita, Bavaro, Luana, De Benedittis, Caterina, Sica, Simona, Sorà, Federica, Iurlo, Alessandra, Bonifacio, Massimiliano, Pregno, Patrizia, Galimberti, Sara, Lunghi, Francesca, Albano, Francesco, D’Adda, Mariella, Crugnola, Monica, Capodanno, Isabella, Castagnetti, Fausto, Gugliotta, Gabriele, Papayannidis, Cristina, Rosti, Gianantonio, Percesepe, Antonio, Mignone, Flavio, Baccarani, Michele, Martinelli, Giovanni, Cavo, Michele
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 01.07.2021
Nature Publishing Group
Subjects
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631/67/1990/283/1896
631/67/1990/283/2125
Acute lymphocytic leukemia
BCR-ABL tyrosine kinase inhibitors
Cancer Research
Chromosomes
Critical Care Medicine
Development and progression
Drug resistance
Drug therapy
Enzyme inhibitors
Gene mutations
Genetic aspects
Hematology
Intensive
Internal Medicine
Kinases
Letter
Leukemia
Leukemia research
Medicine
Medicine & Public Health
Mutation
Oncology
Patients
Philadelphia chromosome
Physiological aspects
Tyrosine
Tyrosine kinase inhibitors
Italy
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Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0887-6924
1476-5551
1476-5551
DOI:10.1038/s41375-020-01098-w