Dynamic functional and ultrastructural changes of gastric parietal cells induced by water immersion-restraint stress in rats

• Published in: World journal of gastroenterology : WJG Vol. 12; no. 21; pp. 3368 - 3372
• Main Authors: Li, Yu-Mei, Lu, Guo-Ming, Zou, Xiao-Ping, Li, Zhao-Shen, Peng, Gui-Yong, Fang, Dian-Chun
• Format: Journal Article
• Language: English
• Published: United States Department of Gastroenterology, Hospital of Zhejiang Armed Police Forces Crops, Jiaxin 314000, Zhejiang Province,China%Department of Pathology, Medical College, Jiaxing University, Jiaxing 314001, Zhejiang Province, China%Department of Gastroenterology of Changhai Hospital, Second Military Medical University,Shanghai 200433, China%Department of Gastroenterology of Southwest Hospital, Third Military Medical University, Chongqing 400038, China 07.06.2006; Baishideng Publishing Group Co., Limited
• Subjects: Animals; Basic Research; Disease Models, Animal; Gastric Acid - metabolism; Gastric Acid - physiology; Gastric Mucosa - enzymology; Gastric Mucosa - pathology; Gastric Mucosa - physiopathology; Gastric Mucosa - ultrastructure; H(+)-K(+)-Exchanging ATPase - analysis; H(+)-K(+)-Exchanging ATPase - physiology; Hydrogen-Ion Concentration; Immersion - adverse effects; Male; Microscopy, Electron; Parietal Cells, Gastric - metabolism; Parietal Cells, Gastric - ultrastructure; Rats; Rats, Sprague-Dawley; Restraint, Physical - adverse effects; Severity of Illness Index; Stomach Ulcer - enzymology; Stomach Ulcer - pathology; Stomach Ulcer - physiopathology; Stomach Ulcer - psychology; Stress, Physiological - pathology; Stress, Physiological - physiopathology; 动力功能; 溃疡疾病; 病理机制; 胃疾病; Sprague-Dawley rat; Stress ulcer; Ultrastructure; Gastric parietal cells; H+,K+-ATPase activity

AIM： To investigate the dynamic functional and ultrastructural changes of gastric parietal cells induced by water immersion-restraint stress （WRS） in rats.METHODS： WRS model of Sprague-Dawley （SD） rats was established. Fifty-six male SD rats were randomly divided into control group, stress group and...