Correlation between the sulfamethoxazole-trimethoprim resistance of Shigella flexneri and the sul genes

• Published in: Medicine (Baltimore) Vol. 100; no. 10; p. e24970
• Main Authors: Ma, Quanping, Zhu, Chengbao, Yao, Mingxiao, Yuan, Guangying, Sun, Yuguo
• Format: Journal Article
• Language: English
• Published: United States Lippincott Williams & Wilkins 12.03.2021
• Subjects: Bacterial Proteins - genetics; Carrier Proteins - genetics; DNA Transposable Elements - genetics; DNA, Bacterial - genetics; DNA, Bacterial - isolation & purification; Dysentery, Bacillary - drug therapy; Dysentery, Bacillary - microbiology; Feces - microbiology; Humans; Microbial Sensitivity Tests; Observational Study; Polymerase Chain Reaction; Shigella flexneri - drug effects; Shigella flexneri - genetics; Shigella flexneri - isolation & purification; Trimethoprim Resistance - genetics; Trimethoprim, Sulfamethoxazole Drug Combination - pharmacology; Trimethoprim, Sulfamethoxazole Drug Combination - therapeutic use

The aim of this study was to discuss the correlation between the sulfamethoxazole-trimethoprim resistance of Shigella flexneri (S. flexneri) and the antibiotic resistance genes sul1, sul2, and sul3 and SXT element.From May 2013 to October 2018, 102 isolates of S. flexneri were collected from the cli...