Chromogranin A as a Marker for Diagnosis, Treatment, and Survival in Patients With Gastroenteropancreatic Neuroendocrine Neoplasm

• Published in: Medicine (Baltimore) Vol. 93; no. 27; p. e247
• Main Authors: Wang, Yu-hong, Yang, Qiu-chen, Lin, Yuan, Xue, Ling, Chen, Min-hu, Chen, Jie
• Format: Journal Article
• Language: English
• Published: United States The Authors. Published by Wolters Kluwer Health, Inc. All rights reserved 01.12.2014; Wolters Kluwer Health
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers - blood; China - epidemiology; Chromogranin A - blood; Digestive System - pathology; Digestive System Neoplasms - blood; Digestive System Neoplasms - mortality; Digestive System Neoplasms - pathology; Female; Humans; Male; Middle Aged; Neuroendocrine Tumors - blood; Neuroendocrine Tumors - mortality; Neuroendocrine Tumors - pathology; Observational Study; Survival Analysis; Young Adult; China
• ISSN: 0025-7974; 1536-5964; 1536-5964
• DOI: 10.1097/MD.0000000000000247

Chromogranin A (CgA) not only plays an important role in pathologic diagnosis, but is also used as a circulating biomarker in patients with gastroenteropancreatic neuroendocrine neoplasm (GEP-NEN). However, the relationship between immunohistochemistry (IHC) expression and serum levels of CgA has no...