Dose-Dependent Flux of Buprenorphine Following Transdermal Administration in Healthy Subjects - Wang, Yi; Cipriano, Alessandra; Munera, Catherine; Harris, Stephen C (Journal of clinical pharmacology, 2016)
Keywords: Administration, Cutaneous; Adult; Analgesics, Opioid - administration & dosage; Analgesics, Opioid - adverse effects; Analgesics, Opioid - pharmacokinetics; Biotransformation; Buprenorphine - administration & dosage; Buprenorphine - adverse effects; Buprenorphine - pharmacokinetics; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Healthy Volunteers; Humans; Male; Transdermal Patch; Young Adult; transdermal delivery system; flux; buprenorphine; absolute bioavailability; dose proportionality