Variant rs6749447 (T > G) in the serine threonine kinase gene is associated with cardiovascular complications, the Tampere adult population cardiovascular risk study

• Published in: Medicine (Baltimore) Vol. 100; no. 42; p. e27566
• Main Authors: Kunnas, Tarja, Määttä, Kirsi, Nikkari, Seppo T.
• Format: Journal Article
• Language: English
• Published: United States Lippincott Williams & Wilkins 22.10.2021
• Subjects: Aged; Body Mass Index; Cardiovascular Diseases - genetics; Cardiovascular Diseases - mortality; Coronary Artery Disease - genetics; Coronary Artery Disease - mortality; Female; Finland - epidemiology; Genetic Predisposition to Disease; Genotype; Heart Disease Risk Factors; Humans; Hypertension - genetics; Hypertension - mortality; Ischemic Attack, Transient - genetics; Ischemic Attack, Transient - mortality; Male; Middle Aged; Mortality, Premature; Observational Study; Polymorphism, Single Nucleotide; Protein Serine-Threonine Kinases - genetics; Finland

We have previously shown an association of STK39 (serine threonine kinase) rs6749447 (T > G) with hypertension in the Tampere adult population cardiovascular risk study in 50-year-old subjects. These 1196 subjects were followed up to the age of 65 years to determine whether rs6749447 is also asso...