Invasive bacterial infections in Gambians with sickle cell anemia in an era of widespread pneumococcal and hemophilus influenzae type b vaccination

• Published in: Medicine (Baltimore) Vol. 95; no. 49; p. e5512
• Main Authors: Soothill, Germander, Darboe, Saffiatou, Bah, Gibril, Bolarinde, Lawal, Cunnington, Aubrey, Anderson, Suzanne T.
• Format: Journal Article
• Language: English
• Published: United States The Authors. Published by Wolters Kluwer Health, Inc. All rights reserved 01.12.2016; Wolters Kluwer Health
• Subjects: Anemia, Sickle Cell; Bacterial Capsules; Bacterial Vaccines - administration & dosage; Female; Gambia - epidemiology; Haemophilus Infections - epidemiology; Haemophilus Infections - etiology; Haemophilus Infections - prevention & control; Haemophilus influenzae type b - immunology; Haemophilus Vaccines - administration & dosage; Humans; Male; Observational Study; Streptococcal Infections - epidemiology; Streptococcal Infections - etiology; Streptococcal Infections - prevention & control; Streptococcus pneumoniae - immunology

There is relatively little data on the etiology of bacterial infections in patients with sickle cell anemia (SCA) in West Africa, and no data from countries that have implemented conjugate vaccines against both Streptococcus pneumoniae and Haemophilus influenzae type b (Hib).We conducted a retrospec...