Hyperhomocysteinemia Exaggerates Adventitial Inflammation and Angiotensin II−Induced Abdominal Aortic Aneurysm in Mice - Liu, Ziyi; Luo, Hongzhi; Zhang, Lu; Huang, Yaqian; Liu, Bo; Ma, Kongyang; Feng, Juan; Xie, Jinsheng; Zheng, Jingang; Hu, Jing; Zhan, Siyan; Zhu, Yi; et al. (Circulation research, 2012)
Keywords: Adventitia - immunology; Angiotensin II - pharmacology; Animals; Aortic Aneurysm, Abdominal - chemically induced; Aortic Aneurysm, Abdominal - epidemiology; Aortic Aneurysm, Abdominal - immunology; Apolipoproteins E - genetics; Biological and medical sciences; Blood and lymphatic vessels; Cardiology. Vascular system; Chemokine CCL2 - secretion; Disease Models, Animal; Diseases of the aorta; Female; Fibroblasts - enzymology; Fibroblasts - immunology; Fibroblasts - secretion; Fundamental and applied biological sciences. Psychology; Humans; Hyperhomocysteinemia - epidemiology; Hyperhomocysteinemia - immunology; Hyperhomocysteinemia - metabolism; Incidence; Interleukin-6 - secretion; Male; Medical sciences; Mice; Mice, Mutant Strains; Middle Aged; NADPH Oxidase 4; NADPH Oxidases - metabolism; Reactive Oxygen Species - metabolism; Risk Factors; Signal Transduction - immunology; Smad2 Protein - metabolism; Smad3 Protein - metabolism; Vasculitis - epidemiology; Vasculitis - immunology; Vasculitis - metabolism; Vasoconstrictor Agents - pharmacology; Vertebrates: cardiovascular system; NADPH; Enzyme; Peptide hormone; Rodentia; Oxidase; Cardiovascular disease; Inflammation; Aortic aneurysm; abdominal aortic aneurysm; Octapeptide; Renin angiotensin system; Vertebrata; adventitial fibroblast; Mammalia; Mouse; NADPH oxidase 4; Hyperhomocysteinemia; Oxidoreductases; Circulatory system; Angiotensin II; Fibroblast