Rapid high-resolution three-dimensional mapping of T1 and age-dependent variations in the non-human primate brain using magnetization-prepared rapid gradient-echo (MPRAGE) sequence

• Published in: NeuroImage (Orlando, Fla.) Vol. 56; no. 3; pp. 1154 - 1163
• Main Authors: Liu, Junjie V., Bock, Nicholas A., Silva, Afonso C.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.06.2011
• Subjects: Aging; Aging - physiology; Algorithms; Animals; Brain - growth & development; Brain - physiology; Brain Mapping - methods; Callithrix; Computer Simulation; Contrast Media; Development; Echo-Planar Imaging - methods; Functional Laterality - physiology; Gadolinium DTPA; Image Processing, Computer-Assisted; Longitudinal relaxation; Magnetic resonance imaging; Models, Statistical; Phantoms, Imaging; Relaxometry; Reproducibility of Results; Aging; Development; Magnetic resonance imaging; Relaxometry; Longitudinal relaxation

The use of quantitative T1 mapping in neuroscience and neurology has raised strong interest in the development of T1-mapping techniques that can measure T1 in the whole brain, with high accuracy and precision and within short imaging and computation times. Here, we present a new inversion-recovery (...