Nucleolar binding of an anti-NMDA receptor antibody in hydra: a non-canonical role for an NMDA receptor protein?

• Published in: Journal of experimental zoology. Part A, Ecological genetics and physiology Vol. 311A; no. 10; pp. 763 - 775
• Main Authors: Kass-Simon, Gabriele, Zompa, Michael A., Scappaticci, Albert A., Zackroff, Robert V., Hufnagel, Linda A.
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.12.2009
• Subjects: Animals; Antibodies, Monoclonal - metabolism; Cell Nucleolus - metabolism; Chromosomal Proteins, Non-Histone - genetics; Chromosomal Proteins, Non-Histone - metabolism; Gene Expression Regulation - physiology; Hydra; Hydra - metabolism; Hydra vulgaris; Immunohistochemistry; Molecular Sequence Data; Nerve Tissue Proteins - genetics; Nerve Tissue Proteins - metabolism; Receptors, N-Methyl-D-Aspartate - genetics; Receptors, N-Methyl-D-Aspartate - metabolism; Sequence Homology; Stem Cells - metabolism; Tissue Distribution

Two emerging concepts in cell biology are the back‐and‐forth trafficking of receptor proteins and nuclear transcription factors between the nucleus and the cell membrane, and the alternative splicing of messenger RNA to produce similar proteins targeted to different cell sites. Recent evidence sugge...