PHoral: Effects of carnosine supplementation on quantity/quality of oral salivae in healthy volunteer and in subjects affected by common oral pathologies

• Published in: Medicine (Baltimore) Vol. 100; no. 25; p. e26369
• Main Authors: Ciulla, Michele M., Re, Dino, Gilardoni, Ettore, D’Amato, Alfonsina, Altomare, Alessandra, Baron, Giovanna, Carugo, Stefano, Aldini, Giancarlo
• Format: Journal Article
• Language: English
• Published: United States Lippincott Williams & Wilkins 25.06.2021
• Subjects: Administration, Buccal; Adolescent; Adult; Cardiovascular Diseases - etiology; Cardiovascular Diseases - prevention & control; Carnosine - administration & dosage; Dental Caries - complications; Dental Caries - diet therapy; Dental Caries - prevention & control; Dietary Supplements; Gingivitis - diet therapy; Gingivitis - microbiology; Gingivitis - prevention & control; Healthy Volunteers; Humans; Hydrogen-Ion Concentration; Male; Microbiota - physiology; Mouth Mucosa - microbiology; Periodontitis - diet therapy; Periodontitis - microbiology; Periodontitis - prevention & control; Saliva - chemistry; Saliva - metabolism; Study Protocol Clinical Trial; Tablets; Young Adult

Diseases of the oral cavity (OC) with an infectious trigger such as caries and periodontal disease are extremely common in the general population and can also have effects at the cardiovascular level. The oral salivary flow, with its buffering capacity, is able to regulate the pH of the OC and, ther...