Association of autonomic symptoms with cerebrospinal fluid biomarkers in Parkinson disease and scans without evidence of dopaminergic deficit

• Published in: Medicine (Baltimore) Vol. 100; no. 7; p. e24837
• Main Authors: Yu, Zhenwei, Li, Yang
• Format: Journal Article
• Language: English
• Published: United States Lippincott Williams & Wilkins 19.02.2021
• Subjects: Aged; Amyloid beta-Peptides - cerebrospinal fluid; Autonomic Nervous System - physiopathology; Autonomic Nervous System Diseases - cerebrospinal fluid; Autonomic Nervous System Diseases - diagnosis; Autonomic Nervous System Diseases - physiopathology; Biomarkers - cerebrospinal fluid; Body Temperature Regulation - physiology; Case-Control Studies; Dopamine - deficiency; Female; Gastrointestinal Diseases - metabolism; Humans; Male; Middle Aged; Observational Study; Parkinson Disease - cerebrospinal fluid; Parkinson Disease - diagnostic imaging; Parkinson Disease - metabolism; Parkinson Disease - physiopathology; Primary Dysautonomias - etiology; Severity of Illness Index; Surveys and Questionnaires; Urologic Diseases - metabolism

Dysautonomia is common in patients with Parkinson disease (PD) since disease early phase. Scales for Outcomes in Parkinson's disease - Autonomic (SCOPA-AUT) is a well-designed scale assessing the autonomic dysfunctions of PD patients. Our objectives were to examine the autonomic dysfunction in...