Circulating long noncoding RNA GAS5 is a novel biomarker for the diagnosis of nonsmall cell lung cancer

• Published in: Medicine (Baltimore) Vol. 95; no. 37; p. e4608
• Main Authors: Liang, Wenjun, Lv, Tangfeng, Shi, Xuefei, Liu, Hongbing, Zhu, Qingqing, Zeng, Junli, Yang, Wen, Yin, Jie, Song, Yong
• Format: Journal Article
• Language: English
• Published: United States The Authors. Published by Wolters Kluwer Health, Inc. All rights reserved 01.09.2016; Wolters Kluwer Health
• Subjects: Adult; Aged; Biomarkers, Tumor - blood; Carcinoma, Non-Small-Cell Lung - blood; Carcinoma, Non-Small-Cell Lung - diagnosis; Carcinoma, Non-Small-Cell Lung - surgery; Case-Control Studies; Diagnostic Accuracy Study; Female; Humans; Lung Neoplasms - blood; Lung Neoplasms - diagnosis; Lung Neoplasms - surgery; Male; Middle Aged; RNA, Long Noncoding - blood

The recently discovered long noncoding RNAs have the potential to regulate many biological processes, which are aberrantly expressed in many tumor types. Our previous study showed that the long noncoding RNA-growth arrest-specific transcript 5 (GAS5) was decreased in lung cancer tissue, which contri...