Focal Parenchymal Atrophy and Fat Replacement Are Clues for Early Diagnosis of Pancreatic Cancer with Abnormalities of the Main Pancreatic Duct

• Published in: The Tohoku Journal of Experimental Medicine Vol. 252; no. 1; pp. 63 - 71
• Main Authors: Ikeda, Mio, Takikawa, Tetsuya, Unno, Michiaki, Sano, Takanori, Yoshida, Naoki, Iseki, Masahiro, Matsumoto, Ryotaro, Furukawa, Toru, Hongo, Seiji, Hamada, Shin, Kume, Kiyoshi, Masamune, Atsushi, Kikuta, Kazuhiro, Tanaka, Yu, Miura, Shin
• Format: Journal Article
• Language: English
• Published: Tohoku University Medical Press 2020
• Subjects: early pancreatic cancer; endoscopic ultrasound; pancreatic intraepithelial neoplasia; pancreatitis; serial pancreatic juice aspiration cytological examination

Pancreatic cancer is one of the most dangerous solid tumors, but its early diagnosis is difficult. The abnormality of the main pancreatic duct (MPD), such as a single localized stricture and upstream dilatation, might be useful in the early detection of pancreatic cancer. However, these findings are...