Chromatin Structure and Dynamics: Focus on Neuronal Differentiation and Pathological Implication

• Published in: Genes Vol. 13; no. 4; p. 639
• Main Authors: Nothof, Sophie A, Magdinier, Frédérique, Van-Gils, Julien
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 02.04.2022; MDPI
• Subjects: Amino acids; Biochemistry, Molecular Biology; Cell cycle; Central nervous system; Chromatin; Chromatin - genetics; Development Biology; DNA methylation; DNA Methylation - genetics; Epigenesis, Genetic; Epigenetics; Gene expression; Genomes; Genomics; Histones; Histones - metabolism; Life Sciences; Molecular weight; Neurobiology; Neurogenesis; Neurons and Cognition; Non-coding RNA; Photoreceptors; Post-translation; Protein Processing, Post-Translational - genetics; Proteins; Review; Translation; acetylation; histone modification; methylation; chromatin; chromatinopathies; epigenetics; neuronal differentiation

Chromatin structure is an essential regulator of gene expression. Its state of compaction contributes to the regulation of genetic programs, in particular during differentiation. Epigenetic processes, which include post-translational modifications of histones, DNA methylation and implication of non-...