Risk Factors Associated With Complications After Unilateral Immediate Breast Reconstruction: A French Prospective Multicenter Study

For women who have undergone a mastectomy, breast reconstruction provides psychological as well as aesthetic benefits. Thus, many patients ask for an immediate breast reconstruction (IBR). The present study focuses on risk factors assiociated with complications after IBR. A national prospective stud...

Full description

Saved in:
Bibliographic Details
Published inIn vivo (Athens) Vol. 35; no. 2; pp. 937 - 945
Main Authors DAUPLAT, JACQUES, THIVAT, EMILIE, ROUANET, PHILIPPE, DELAY, EMMANUEL, CLOUGH, KRISHNA, VERHAEGHE, JEAN-LUC, RAOUST, INES, BANNIER, MARIE, LEMASURIER, PERIG, POMEL, CHRISTOPHE
Format Journal Article
LanguageEnglish
Published Greece International Institute of Anticancer Research 01.03.2021
International Institute of Anticancer Research (IIAR)
Subjects
Biopsy
Breast cancer
Cancer
Cancer therapies
Chemotherapy
Diabetes
Dissection
Health risks
Hematoma
Hospitalization
Intervention
Life Sciences
Lymphatic system
Lymphedema
Mastectomy
Multivariate analysis
Obesity
Overweight
Pain
Patients
Radiation therapy
Skin
Surgery
Surgical outcomes
Tumors
Wound dehiscence
risk factors
Breast cancer
mastectomy
complications
morbidity
breast reconstruction
Online AccessGet full text

Cover

Abstract For women who have undergone a mastectomy, breast reconstruction provides psychological as well as aesthetic benefits. Thus, many patients ask for an immediate breast reconstruction (IBR). The present study focuses on risk factors assiociated with complications after IBR. A national prospective study (2007-2009) was conducted on 404 patients who underwent an unilateral IBR: 205 implants alone (IA) including 46 tissue expanders, 91 latissimus dorsi musculocutaneous flaps with implant (LDI), 78 autologous latissimus dorsi musculocutaneous flaps (LD), and 30 autologous transverse rectus abdominis musculocutaneous flaps (TRAM). Outcomes concerned major and minor complications, as well as early and late complications. Related risks of complications were different according to the IBR technique. Major complications rate remained moderate and concerned 15% of patients. Obesity and diabetes significantly increased the incidence of major complications. To reduce complication rate, the risk factors associated with each type of IBR should be taken into account.
AbstractList Background/Aim: For women who have undergone a mastectomy, breast reconstruction provides psychological as well as aesthetic benefits. Thus, many patients ask for an immediate breast reconstruction (IBR). The present study focuses on risk factors assiociated with complications after IBR. Patients and Methods: A national prospective study (2007-2009) was conducted on 404 patients who underwent an unilateral IBR: 205 implants alone (IA) including 46 tissue expanders, 91 latissimus dorsi musculocutaneous flaps with implant (LDI), 78 autologous latissimus dorsi musculocutaneous flaps (LD), and 30 autologous transverse rectus abdominis musculocutaneous flaps (TRAM). Outcomes concerned major and minor complications, as well as early and late complications. Results: Related risks of complications were different according to the IBR technique. Major complications rate remained moderate and concerned 15% of patients. Obesity and diabetes significantly increased the incidence of major complications. Conclusion: To reduce complication rate, the risk factors associated with each type of IBR should be taken into account.
For women who have undergone a mastectomy, breast reconstruction provides psychological as well as aesthetic benefits. Thus, many patients ask for an immediate breast reconstruction (IBR). The present study focuses on risk factors assiociated with complications after IBR. A national prospective study (2007-2009) was conducted on 404 patients who underwent an unilateral IBR: 205 implants alone (IA) including 46 tissue expanders, 91 latissimus dorsi musculocutaneous flaps with implant (LDI), 78 autologous latissimus dorsi musculocutaneous flaps (LD), and 30 autologous transverse rectus abdominis musculocutaneous flaps (TRAM). Outcomes concerned major and minor complications, as well as early and late complications. Related risks of complications were different according to the IBR technique. Major complications rate remained moderate and concerned 15% of patients. Obesity and diabetes significantly increased the incidence of major complications. To reduce complication rate, the risk factors associated with each type of IBR should be taken into account.
Background/Aim: For women who have undergone a mastectomy, breast reconstruction provides psychological as well as aesthetic benefits. Thus, many patients ask for an immediate breast reconstruction (IBR). The present study focuses on risk factors assiociated with complications after IBR. Patients and Methods: A national prospective study (2007-2009) was conducted on 404 patients who underwent an unilateral IBR: 205 implants alone (IA) including 46 tissue expanders, 91 latissimus dorsi musculocutaneous flaps with implant (LDI), 78 autologous latissimus dorsi musculo-cutaneous flaps (LD), and 30 autologous transverse rectus abdominis musculocutaneous flaps (TRAM). Outcomes concerned major and minor complications, as well as early and late complications. Results: Related risks of complications were different according to the IBR technique. Major complications rate remained moderate and concerned 15% of patients. Obesity and diabetes significantly increased the incidence of major complications. Conclusion: To reduce complication rate, the risk factors associated with each type of IBR should be taken into account.
For women who have undergone a mastectomy, breast reconstruction provides psychological as well as aesthetic benefits. Thus, many patients ask for an immediate breast reconstruction (IBR). The present study focuses on risk factors assiociated with complications after IBR.BACKGROUND/AIMFor women who have undergone a mastectomy, breast reconstruction provides psychological as well as aesthetic benefits. Thus, many patients ask for an immediate breast reconstruction (IBR). The present study focuses on risk factors assiociated with complications after IBR.A national prospective study (2007-2009) was conducted on 404 patients who underwent an unilateral IBR: 205 implants alone (IA) including 46 tissue expanders, 91 latissimus dorsi musculocutaneous flaps with implant (LDI), 78 autologous latissimus dorsi musculocutaneous flaps (LD), and 30 autologous transverse rectus abdominis musculocutaneous flaps (TRAM). Outcomes concerned major and minor complications, as well as early and late complications.PATIENTS AND METHODSA national prospective study (2007-2009) was conducted on 404 patients who underwent an unilateral IBR: 205 implants alone (IA) including 46 tissue expanders, 91 latissimus dorsi musculocutaneous flaps with implant (LDI), 78 autologous latissimus dorsi musculocutaneous flaps (LD), and 30 autologous transverse rectus abdominis musculocutaneous flaps (TRAM). Outcomes concerned major and minor complications, as well as early and late complications.Related risks of complications were different according to the IBR technique. Major complications rate remained moderate and concerned 15% of patients. Obesity and diabetes significantly increased the incidence of major complications.RESULTSRelated risks of complications were different according to the IBR technique. Major complications rate remained moderate and concerned 15% of patients. Obesity and diabetes significantly increased the incidence of major complications.To reduce complication rate, the risk factors associated with each type of IBR should be taken into account.CONCLUSIONTo reduce complication rate, the risk factors associated with each type of IBR should be taken into account.
Author THIVAT, EMILIE
ROUANET, PHILIPPE
BANNIER, MARIE
DAUPLAT, JACQUES
LEMASURIER, PERIG
POMEL, CHRISTOPHE
DELAY, EMMANUEL
CLOUGH, KRISHNA
VERHAEGHE, JEAN-LUC
RAOUST, INES
Author_xml – sequence: 1
  givenname: JACQUES
  surname: DAUPLAT
  fullname: DAUPLAT, JACQUES
– sequence: 2
  givenname: EMILIE
  surname: THIVAT
  fullname: THIVAT, EMILIE
– sequence: 3
  givenname: PHILIPPE
  surname: ROUANET
  fullname: ROUANET, PHILIPPE
– sequence: 4
  givenname: EMMANUEL
  surname: DELAY
  fullname: DELAY, EMMANUEL
– sequence: 5
  givenname: KRISHNA
  surname: CLOUGH
  fullname: CLOUGH, KRISHNA
– sequence: 6
  givenname: JEAN-LUC
  surname: VERHAEGHE
  fullname: VERHAEGHE, JEAN-LUC
– sequence: 7
  givenname: INES
  surname: RAOUST
  fullname: RAOUST, INES
– sequence: 8
  givenname: MARIE
  surname: BANNIER
  fullname: BANNIER, MARIE
– sequence: 9
  givenname: PERIG
  surname: LEMASURIER
  fullname: LEMASURIER, PERIG
– sequence: 10
  givenname: CHRISTOPHE
  surname: POMEL
  fullname: POMEL, CHRISTOPHE
BackLink https://www.ncbi.nlm.nih.gov/pubmed/33622886$$D View this record in MEDLINE/PubMed
https://hal.science/hal-03223687$$DView record in HAL
BookMark eNp1kk1vEzEQhi1URNPCkSuyxIUetvhzd80BKUQNrRQEKlRws7zeWeKyWQfbG6ln_jhOUiqIxMWWZp555_MEHQ1-AISeU3LOaF3x127YuI0_p4xz8QhNaKVoUUmhjtCEMFkXtaTfjtFJjLeElBUh7Ak65rxkrK7LCfp17eIPPDc2-RDxNEZvnUnQ4q8uLfHMr9a9syY5P2RvlyDgm8H1mQimx1erFbRbHL8LYGLC12AzmMJotxFv8BTPAwx2iT8FH9eQrRvAH8Y-OQvDVuxzGtu7p-hxZ_oIz-7_U3Qzv_gyuywWH99fzaaLwgqhUmFEQzvZlg0QqKhh0rBSVUw1wGktOtmVoAxYUUIrlWppwylU-elaq5RsFD9Fb_e667HJhW9LyF3odXArE-60N07_6xncUn_3G10TIYliWeBsL7A8CLucLvTWRjhjvKyrDc3sq_tkwf8cISa9ctFC35sB_Bg1E4oTQiUrM_ryAL31YxjyKDRnnIiKKyEz9eLv6h_y_9llBoo9YPOwY4DuAaFE725F729F724l8_yAty7tVp2bd_1_on4DmRjGug
CitedBy_id crossref_primary_10_1007_s00266_022_03121_0
crossref_primary_10_25122_jml_2022_0227
crossref_primary_10_1016_j_bjps_2024_07_046
crossref_primary_10_1097_GOX_0000000000004693
crossref_primary_10_1016_j_clbc_2025_01_001
crossref_primary_10_7888_juoeh_45_199
crossref_primary_10_55453_rjmm_2025_128_1_6
crossref_primary_10_1097_GOX_0000000000004180
ContentType Journal Article
Copyright Copyright© 2021, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.
2021. This work is published under https://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Distributed under a Creative Commons Attribution 4.0 International License
Copyright 2021, International Institute of Anticancer Research 2021
Copyright_xml – notice: Copyright© 2021, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.
– notice: 2021. This work is published under https://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
– notice: Distributed under a Creative Commons Attribution 4.0 International License
– notice: Copyright 2021, International Institute of Anticancer Research 2021
CorporateAuthor the STIC-RMI Working Group
STIC-RMI Working Group
CorporateAuthor_xml – name: the STIC-RMI Working Group
– name: STIC-RMI Working Group
DBID AAYXX
CITATION
NPM
3V.
7RV
7X7
7XB
88E
8FI
8FJ
8FK
ABUWG
AFKRA
BENPR
CCPQU
FYUFA
GHDGH
K9.
KB0
M0S
M1P
NAPCQ
PHGZM
PHGZT
PJZUB
PKEHL
PPXIY
PQEST
PQQKQ
PQUKI
7X8
1XC
5PM
DOI 10.21873/invivo.12334
DatabaseName CrossRef
PubMed
ProQuest Central (Corporate)
Nursing & Allied Health Database
Health & Medical Collection
ProQuest Central (purchase pre-March 2016)
Medical Database (Alumni Edition)
ProQuest Hospital Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
ProQuest Central (Alumni)
ProQuest Central UK/Ireland
ProQuest Central
ProQuest One
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Health & Medical Complete (Alumni)
Nursing & Allied Health Database (Alumni Edition)
ProQuest Health & Medical Collection
Medical Database
Nursing & Allied Health Premium
ProQuest Central Premium
ProQuest One Academic
ProQuest Health & Medical Research Collection
ProQuest One Academic Middle East (New)
ProQuest One Health & Nursing
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic
ProQuest One Academic UKI Edition
MEDLINE - Academic
Hyper Article en Ligne (HAL)
PubMed Central (Full Participant titles)
DatabaseTitle CrossRef
PubMed
ProQuest One Academic Middle East (New)
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
ProQuest One Community College
ProQuest One Health & Nursing
ProQuest Central
ProQuest Health & Medical Research Collection
Health Research Premium Collection
Health and Medicine Complete (Alumni Edition)
Health & Medical Research Collection
ProQuest Central (New)
ProQuest Medical Library (Alumni)
ProQuest One Academic Eastern Edition
ProQuest Nursing & Allied Health Source
ProQuest Hospital Collection
Health Research Premium Collection (Alumni)
ProQuest Hospital Collection (Alumni)
Nursing & Allied Health Premium
ProQuest Health & Medical Complete
ProQuest Medical Library
ProQuest One Academic UKI Edition
ProQuest Nursing & Allied Health Source (Alumni)
ProQuest One Academic
ProQuest One Academic (New)
ProQuest Central (Alumni)
MEDLINE - Academic
DatabaseTitleList ProQuest One Academic Middle East (New)
PubMed

MEDLINE - Academic
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: BENPR
  name: ProQuest Central
  url: https://www.proquest.com/central
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
EISSN 1791-7549
EndPage 945
ExternalDocumentID PMC8045092
oai_HAL_hal_03223687v1
33622886
10_21873_invivo_12334
Genre Journal Article
GroupedDBID ---
53G
5GY
5VS
AAYXX
AENEX
AFOSN
ALMA_UNASSIGNED_HOLDINGS
CITATION
DIK
EBS
EJD
EMOBN
F5P
H13
HYE
KQ8
OK1
P2P
RHI
RPM
VRB
W8F
NPM
3V.
7RV
7X7
7XB
88E
8FI
8FJ
8FK
ABUWG
AFKRA
BENPR
CCPQU
FYUFA
HMCUK
K9.
M1P
NAPCQ
PHGZM
PHGZT
PJZUB
PKEHL
PPXIY
PQEST
PQQKQ
PQUKI
PSQYO
UKHRP
7X8
1XC
5PM
ID FETCH-LOGICAL-c449t-a4b1f5d6be0e71a25a269729be3184f5f6e9aec46ed599d1b31e7b31fdc995b93
IEDL.DBID 7X7
ISSN 0258-851X
1791-7549
IngestDate Thu Aug 21 13:32:18 EDT 2025
Wed Aug 13 07:45:24 EDT 2025
Tue Aug 05 10:15:21 EDT 2025
Thu Jul 31 08:40:36 EDT 2025
Mon Jul 21 05:34:17 EDT 2025
Tue Jul 01 04:24:41 EDT 2025
Thu Apr 24 23:09:22 EDT 2025
IsDoiOpenAccess false
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 2
Keywords risk factors
Breast cancer
mastectomy
complications
morbidity
breast reconstruction
Language English
License Copyright© 2021, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.
Distributed under a Creative Commons Attribution 4.0 International License: http://creativecommons.org/licenses/by/4.0
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c449t-a4b1f5d6be0e71a25a269729be3184f5f6e9aec46ed599d1b31e7b31fdc995b93
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
PMCID: PMC8045092
ORCID 0000-0003-0415-3269
OpenAccessLink https://iv.iiarjournals.org/content/invivo/35/2/937.full.pdf
PMID 33622886
PQID 3230473945
PQPubID 7212310
PageCount 9
ParticipantIDs pubmedcentral_primary_oai_pubmedcentral_nih_gov_8045092
hal_primary_oai_HAL_hal_03223687v1
proquest_miscellaneous_2493001526
proquest_journals_3230473945
pubmed_primary_33622886
crossref_primary_10_21873_invivo_12334
crossref_citationtrail_10_21873_invivo_12334
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 2021-03-01
PublicationDateYYYYMMDD 2021-03-01
PublicationDate_xml – month: 03
  year: 2021
  text: 2021-03-01
  day: 01
PublicationDecade 2020
PublicationPlace Greece
PublicationPlace_xml – name: Greece
– name: Highlands
PublicationTitle In vivo (Athens)
PublicationTitleAlternate In Vivo
PublicationYear 2021
Publisher International Institute of Anticancer Research
International Institute of Anticancer Research (IIAR)
Publisher_xml – name: International Institute of Anticancer Research
– name: International Institute of Anticancer Research (IIAR)
SSID ssj0067002
Score 2.3374877
Snippet For women who have undergone a mastectomy, breast reconstruction provides psychological as well as aesthetic benefits. Thus, many patients ask for an immediate...
Background/Aim: For women who have undergone a mastectomy, breast reconstruction provides psychological as well as aesthetic benefits. Thus, many patients ask...
SourceID pubmedcentral
hal
proquest
pubmed
crossref
SourceType Open Access Repository
Aggregation Database
Index Database
Enrichment Source
StartPage 937
SubjectTerms Biopsy
Breast cancer
Cancer
Cancer therapies
Chemotherapy
Diabetes
Dissection
Health risks
Hematoma
Hospitalization
Intervention
Life Sciences
Lymphatic system
Lymphedema
Mastectomy
Multivariate analysis
Obesity
Overweight
Pain
Patients
Radiation therapy
Skin
Surgery
Surgical outcomes
Tumors
Wound dehiscence
Title Risk Factors Associated With Complications After Unilateral Immediate Breast Reconstruction: A French Prospective Multicenter Study
URI https://www.ncbi.nlm.nih.gov/pubmed/33622886
https://www.proquest.com/docview/3230473945
https://www.proquest.com/docview/2493001526
https://hal.science/hal-03223687
https://pubmed.ncbi.nlm.nih.gov/PMC8045092
Volume 35
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lb9QwELZoKyEuCMqjKaUyCHEiNLGdh7mg7WO1BVpVFRV7i2zH0UZsk8KmK_XMH2fGebQLgkukxE5iefz4xvPNDCFvdJgmGBXcF5JZX3DDkQRgfK4sV4HKbegO3E5O48mF-DSNpt2B26KjVfZroluo89rgGfkedwYiLkX08eqHj1mj0LrapdBYIxsYugwpXcl0ULjQA8VZEViU-oAspm2MTdjUEr5XVstyWb-HhZuLlT1pbYaMyL_h5p-syTvb0PgRedjhRzpqBf6Y3LPVJrl_0lnIn5Bf5-XiOx23WXRo3_k2p9_KZkYP7hLI6Qjzg1NAnXOFfshzenzpHEkaS_eRq95QVE5vQ8x-oCM6Ru_AGT37Wfc-mtT58GJz4WNIS7x5Si7GR18PJn6XaME3QsjGV0KHRZTH2gY2CRWLFIsloG6NB6SiiIrYSmWNiG0eSZmHmoc2gUuRGykjLfkzsl7Vld0iVIF6aQS8EfFC6CKVJtWaS21kEiTGMI-867s6M10UckyGMc9AG3GSyVrJZE4yHnk7VL9qw2_8q-JrkNtQB4NmT0ZfMnwWwJrF4zRZhh7Z6cWadVN1kd0OLI-8GophkqHlRFW2vl5koKNyRJcs9sjzdhQMv-IAAViaQkmyMj5W2rJaUpUzF8g7BTwdSLb9_2a9IA8YEmkc8W2HrIPQ7UtAQo3edcN9l2zsH52encPd4fHn3zC3Dkc
linkProvider ProQuest
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1LbxMxELZKKgEXxJuFAgYBJ5bu2t6HkRBKS6OEJlFVtWpui-31KivCbiEhqGf-D7-RmX2kDQhuveQQexNrZzz-xvPNDCEvtB9HWBXcFZJZV3DDkQRgXK4sV55KrV9duI3GYf9YfJwEkw3yq82FQVplaxMrQ52WBu_It3kVIOJSBO9Pv7rYNQqjq20LjVot9u3ZD3DZ5u8GH0C-Lxnr7R3t9t2mq4BrhJALVwntZ0EaauvZyFcsUCyUADE13gaKLMhCK5U1IrRpIGXqa-7bCD6y1EgZaCy-BCZ_U3BwZTpkc2dvfHDY2n7MeaniFiyIXcAyk7qqJxyjEd_Oi2W-LN_AUcHF2il4ZYoczL8B7p88zQsHX-8mudEgVtqtVewW2bDFbXJ11MTk75Cfh_n8M-3VfXtoK26b0pN8MaW7FynrtIsdySng3JnCzOcZHXypUlcWlu4gO35B0R0-L2r7lnZpD_MRp_TgW9lmhdIqaxiXCz-GRMizu-T4UoRwj3SKsrAPCFXg0BoBTwQ8EzqLpYm15lIbGXmRMcwhr9tXnZim7jm235gl4P9UkklqySSVZBzyajX9tC748a-Jz0FuqzlYprvfHSb4nQdWkodxtPQdstWKNWmMwzw5V2WHPFsNw7bGWI0qbPl9noBXzBHPstAh92stWP0VB9DB4hhGojX9WFvL-kiRT6vS4TEgeE-yh_9f1lNyrX80GibDwXj_EbnOkMZT0e62SAcUwD4GHLbQTxrlp-TTZe-335zzSwk
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Risk+Factors+Associated+With+Complications+After+Unilateral+Immediate+Breast+Reconstruction%3A+A+French+Prospective+Multicenter+Study&rft.jtitle=In+vivo+%28Athens%29&rft.au=Dauplat%2C+Jacques&rft.au=Thivat%2C+Emilie&rft.au=Rouanet%2C+Philippe&rft.au=Delay%2C+Emmanuel&rft.date=2021-03-01&rft.pub=International+Institute+of+Anticancer+Research+%28IIAR%29&rft.issn=0258-851X&rft.volume=35&rft.issue=2&rft.spage=937&rft.epage=945&rft_id=info:doi/10.21873%2Finvivo.12334&rft.externalDBID=HAS_PDF_LINK&rft.externalDocID=oai_HAL_hal_03223687v1
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0258-851X&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0258-851X&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0258-851X&client=summon