SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo - Hou, Yixuan J.; Chiba, Shiho; Halfmann, Peter; Ehre, Camille; Kuroda, Makoto; Dinnon, Kenneth H.; Leist, Sarah R.; Schäfer, Alexandra; Nakajima, Noriko; Takahashi, Kenta; Lee, Rhianna E.; Mascenik, Teresa M.; et al. (Science (American Association for the Advancement of Science), 2020)
Keywords: ACE2; Amino Acid Substitution; Angiotensin-converting enzyme 2; Angiotensin-Converting Enzyme 2 - genetics; Animal models; Animals; Asparagine - genetics; Aspartic acid; Coronaviridae; Coronaviruses; COVID-19; COVID-19 - transmission; COVID-19 - virology; Cricetinae; Disease transmission; Fitness; Genetic Fitness - genetics; Glycine; Glycine - genetics; Hamsters; Humans; Mesocricetus; Mice; Mice, Transgenic; Microbio; Morphology; Mutation; Neutralization; Pandemics; Pathogenesis; Pathogens; Replication; Respiratory diseases; Respiratory Mucosa - virology; Rodents; SARS-CoV-2 - genetics; SARS-CoV-2 - pathogenicity; Severe acute respiratory syndrome coronavirus 2; Substitutes; Viral diseases; Virulence; Virulence - genetics; Virus Replication - genetics; Viruses