PopLDdecay: a fast and effective tool for linkage disequilibrium decay analysis based on variant call format files

• Published in: Bioinformatics Vol. 35; no. 10; pp. 1786 - 1788
• Main Authors: Zhang, Chi, Dong, Shan-Shan, Xu, Jun-Yang, He, Wei-Ming, Yang, Tie-Lin
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 15.05.2019
• Subjects: bioinformatics; computer software; genome; linkage disequilibrium

Abstract Motivation Linkage disequilibrium (LD) decay is of great interest in population genetic studies. However, no tool is available now to do LD decay analysis from variant call format (VCF) files directly. In addition, generation of pair-wise LD measurements for whole genome SNPs usually result...