Benzo[a]pyrene toxicokinetics in humans following dietary supplementation with 3,3′-diindolylmethane (DIM) or Brussels sprouts - Vermillion Maier, Monica L.; Siddens, Lisbeth K.; Pennington, Jamie M.; Uesugi, Sandra L.; Tilton, Susan C.; Vertel, Emily A.; Anderson, Kim A.; Tidwell, Lane G.; Ognibene, Ted J.; Turteltaub, Kenneth W.; Smith, Jordan N.; Williams, David E. (Toxicology and applied pharmacology, 2023)
Keywords: 3,3’-diindolylmethane; Accelerator mass spectrometry; Benzo(a)pyrene; Brussels sprouts; Carcinogens; Dietary Supplements; Human carcinogen dosing; Humans; Toxicokinetics; BaP-7,8-DHD; FDA IND; DBC; CHL; PBPK; Accelerator mass spectrometry; RPF; AFB1; AHR; NPL; N2-dG; AUC; BaP; BR-DIM; Brussels sprouts; US EPA; Benzo[a]pyrene; PhIP; CYP; LLNL; BMI; LOD; Cmax; BaP-DHDE; AMS; IQ; DIM; HCC; IARC; PBMC; LOQ; Toxicokinetics; OSU; MeIQx; ATSDR; IPCS; UPLC; PAH; Tmax; IRB; JEFCA; Human carcinogen dosing; 3,3’-diindolylmethane