A Triple Mystery of Insidious Organ Failure: Are the Lung, Kidney and Brain All Damaged by the Ageing Pulse?

• Published in: Biomedicines Vol. 12; no. 9; p. 1969
• Main Authors: Stone, Jonathan, Robinson, Stephen R, Mitrofanis, John, Johnstone, Daniel M
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.09.2024; MDPI
• Subjects: Aging; Blood vessels; Brain; Brain damage; Capillaries; capillary haemorrhage; chronic kidney disease; Chronic kidney failure; Dementia; Dementia disorders; Development and progression; Failure; Fibrosis; healthy ageing; Hemorrhage; Hypertension; idiopathic pulmonary fibrosis; Kidney diseases; Lung diseases; Lungs; Medical treatment; Middle age; Neuropathology; Pathology; Proteins; Pulmonary fibrosis; Renal failure; Renal function; Review; Australia; capillary haemorrhage; dementia; chronic kidney disease; idiopathic pulmonary fibrosis; hypertension; healthy ageing

This review explores the hypothesis that dementia in several forms, chronic kidney disease and idiopathic pulmonary fibrosis have a common cause in pulse-induced capillary haemorrhage. All three conditions are age-related and characterised by insidious onset, uncertainty about their cause, exacerbat...