Identification of microRNA expression profile related to lymph node status in women with early-stage grade 1–2 endometrial cancer

• Published in: Modern pathology Vol. 29; no. 4; pp. 391 - 401
• Main Authors: Canlorbe, Geoffroy, Wang, Zhe, Laas, Enora, Bendifallah, Sofiane, Castela, Mathieu, Lefevre, Marine, Chabbert-Buffet, Nathalie, Daraï, Emile, Aractingi, Selim, Méhats, Céline, Ballester, Marcos
• Format: Journal Article
• Language: English
• Published: New York Nature Publishing Group US 01.04.2016; Elsevier Limited; Nature Publishing Group: Open Access Hybrid Model Option B
• Subjects: 38/61; 38/77; 692/699/67/1517/1931; Aged; Biomarkers, Tumor - analysis; Biomarkers, Tumor - genetics; Cancer; Carcinoma, Endometrioid - genetics; Carcinoma, Endometrioid - pathology; Endometrial Neoplasms - genetics; Endometrial Neoplasms - pathology; Female; Gynecology and obstetrics; Human health and pathology; Humans; Laboratory Medicine; Life Sciences; Lymphatic Metastasis - genetics; Lymphatic Metastasis - pathology; Medicine; Medicine & Public Health; MicroRNAs - analysis; Middle Aged; Neoplasm Staging - methods; Oligonucleotide Array Sequence Analysis; original-article; Pathology; Polymerase Chain Reaction; Transcriptome

Conventional methods used for histologic classification and grading of endometrial cancer (EC) are not sufficient to predict lymph node metastases. microRNA signatures have recently been related to EC pathologic characteristics or prognosis. The aim of this study was to evaluate whether microRNA pro...