Core-Shell Upconversion Nanoparticle@Metal-Organic Framework Nanoprobes for Luminescent/Magnetic Dual-Mode Targeted Imaging

• Published in: Advanced materials (Weinheim) Vol. 27; no. 27; pp. 4075 - 4080
• Main Authors: Li, Yantao, Tang, Jinglong, He, Liangcan, Liu, Yong, Liu, Yaling, Chen, Chunying, Tang, Zhiyong
• Format: Journal Article
• Language: English
• Published: Germany Blackwell Publishing Ltd 15.07.2015
• Subjects: Animals; biocompatibility; Biocompatible Materials - chemical synthesis; Biocompatible Materials - chemistry; Cell Line, Tumor; Cell Survival; Contrast Media - chemical synthesis; Contrast Media - chemistry; core-shell nanostructures; dual-mode targeted imaging; Humans; Luminescence; Luminescent Measurements - instrumentation; Luminescent Measurements - methods; Magnetic Resonance Imaging - instrumentation; Magnetic Resonance Imaging - methods; Magnetite Nanoparticles - chemistry; Mice, Inbred BALB C; Mice, Nude; Microscopy, Confocal; Microscopy, Electron, Transmission; Neoplasm Transplantation; Polyethylene Glycols - chemistry; Spectrum Analysis; surface modification; Water - chemistry; X-Ray Diffraction; core-shell nanostructures; dual-mode targeted imaging; biocompatibility; surface modification

Core–shell upconversion nanoparticle@metal–organic framework (UCNP@MOF) nanostructures are constructed by coating hexagonal NaYF4:Yb,Er nanoparticle (NP) cores with amino‐functionalized iron carboxylate MOF shells. These nanostructures combine the near‐infrared optical property of the UCNP cores and...