Immunometabolism at the crossroads of obesity and cancer—a Keystone Symposia report

• Published in: Annals of the New York Academy of Sciences Vol. 1523; no. 1; pp. 38 - 50
• Main Authors: Cable, Jennifer, Rathmell, Jeffrey C., Pearce, Erika L., Ho, Ping‐Chih, Haigis, Marcia C., Mamedov, Murad R., Wu, Meng‐Ju, Kaech, Susan M., Lynch, Lydia, Febbraio, Mark A., Bapat, Sagar P., Hong, Hanna S., Zou, Weiping, Belkaid, Yasmine, Sullivan, Zuri A., Keller, Andrea, Wculek, Stefanie K., Green, Douglas R., Postic, Catherine, Amit, Ido, Benitah, Salvador Aznar, Jones, Russell G., Reina‐Campos, Miguel, Torres, Santiago Valle, Beyaz, Semir, Brennan, Donal, O'Neill, Luke A. J., Perry, Rachel J., Brenner, Dirk
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.05.2023
• Subjects: Cancer; Humans; Immune System; Immunity; immunometabolism; immunotherapy; Metabolic Networks and Pathways; Metabolic pathways; Metabolism; Microbiomes; Neoplasms - metabolism; New technology; Obesity; Obesity - metabolism; Obesity - therapy; Pathogenesis; Therapeutic targets; Tumor cells; Tumor Microenvironment; Tumors; cancer; metabolism; immunity; immunometabolism; obesity; immunotherapy

Immunometabolism considers the relationship between metabolism and immunity. Typically, researchers focus on either the metabolic pathways within immune cells that affect their function or the impact of immune cells on systemic metabolism. A more holistic approach that considers both these viewpoint...