Association of biological age with health outcomes and its modifiable factors

• Published in: Aging cell Vol. 22; no. 12; pp. e13995 - n/a
• Main Authors: Liu, Wei‐Shi, You, Jia, Ge, Yi‐Jun, Wu, Bang‐Sheng, Zhang, Yi, Chen, Shi‐Dong, Zhang, Ya‐Ru, Huang, Shu‐Yi, Ma, Ling‐Zhi, Feng, Jian‐Feng, Cheng, Wei, Yu, Jin‐Tai
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.12.2023; John Wiley and Sons Inc
• Subjects: Age differences; Aging; Aging - genetics; Algorithms; Biobanks; biological age; Blood pressure; Body mass; Brain; C-reactive protein; Cardiovascular Diseases; Child, Preschool; Chronic obstructive pulmonary disease; Cognitive ability; disease; Ethnicity; Genetic analysis; Glomerular filtration rate; Growth factors; Hand Strength; Humans; Metabolic rate; modifiable factor; Mortality; Outcome Assessment, Health Care; Physiology; Regression analysis; Therapeutic targets; unmodifiable factor; United Kingdom > UK; Aging; mortality; disease; biological age; modifiable factor; unmodifiable factor

Identifying the clinical implications and modifiable and unmodifiable factors of aging requires the measurement of biological age (BA) and age gap. Leveraging the biomedical traits involved with physical measures, biochemical assays, genomic data, and cognitive functions from the healthy participant...